Study for comparison of bupivacaine alone bupivacaine plus dexmedetomidine and bupivacaine plus magnesium sulfate for prevention of shivering after spinal anaesthesia in prostate surgery.
- Conditions
- Benign prostatic hyperplasia withlower urinary tract symptoms,
- Registration Number
- CTRI/2021/01/030305
- Lead Sponsor
- Dr SN Medical college and associated group of hospitals Jodhpur
- Brief Summary
This study " A comparative study to assess the efficacy and safety of intrathecal bupivacaine alone, intrathecal bupivacaine plus dexmedetomidine and intrathecal bupivacaine plus magnesium sulfate for the prevention of post spinal anaesthesia shivering in transurethral resection of prostate (TURP)" will be done at Dr SN Medical college and associated group of hospitals Jodhpur (Rajasthan), after obtaining informed consent from the patients, under the guidance of my guide and the study is approved by institutional ethical committee -Dr Sampurnanand Medical College Jodhpur. There will be no financial burdon on the patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Male
- Target Recruitment
- 75
Male patients of ASA grade I and II of age 18-60 years posted for transurethral resection of prostate suitable for administration of regional anaesthesia.
Patients refusal, BMI>28.0, spinal abnormality, patients with CKD, any contraindication to spinal anaesthesia like sepsis, abnormal coagulation profile, emergency surgery, infection at site of injection, allergy to local anaesthetics.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of intrathecal bupivacaine alone, bupivacaine plus dexmedetomidine and bupivacaine plus magnesium sulfate group in terms of incidence and intensity of shivering 3 Months
- Secondary Outcome Measures
Name Time Method To compare the safety of intrathecal bupivacaine alone, bupivacaine plus dexmedetomidine and bupivacaine plus magnesium sulfate group in terms of hypothermia sedation score and complication including hypotension, bradycardia, nausea, vomiting and total dose of pethidine required to control shivering 3 months
Trial Locations
- Locations (1)
Dr SN Medical college and associated group of hospitals Jodhpur
🇮🇳Jodhpur, RAJASTHAN, India
Dr SN Medical college and associated group of hospitals Jodhpur🇮🇳Jodhpur, RAJASTHAN, IndiaDr Sunil Kumar SaharanPrincipal investigator9462322433sunilksaharan@gmail.com