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A Randomized controlled Clinical Trial to determine the efficacy of Siddha drugs in COVID 19 patients

Phase 2/3
Completed
Conditions
Coronavirus as the cause of diseases classified elsewhere,
Registration Number
CTRI/2020/06/025763
Lead Sponsor
National institute of Siddha
Brief Summary

There is a sudden outbreak of Novel Coronavirus disease all over the world. As there is no direct drug against the disease spread, it is a time needed action of usage of AYUSH drugs in management. Various drugs have been cited by AYUSH ministry and State government for management of the disease spread like Kabasura kudineer, Amukkara choornam etc. This study will be conducted based on the Preliminary analysis and literature evidence of drugs namely Kabasura kudineer, Amukkara choornam, Thalisathi choornam and Adathodai manapaggu, Maldevi chenduram, Thippili rasayanam etc.  among the sample consists of 18 years and above COVID-19 – RT PCR +ve patients declared by Tamil Nadu Government accredited labs admitted to COVID 19 ward at SRMMCH / NIS or quarantined Govt. facilities or at home quarantine. The subjects will be randomly allocated to both the test or control groups. This study is carried out to analyze document scientifically the therapeutic efficacy of these drugs against Novel Corona virus disease.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
150
Inclusion Criteria
  • Male, Female and Transgenders.
  • ï‚· Age between 18 to 85 years ï‚· COVID 19 positive asymptomatic / pre symptomatic, mild and moderately and severely symptomatic patients.
  • ï‚· Willing to consent to the study.
Exclusion Criteria
  • High risk groups (Patients with Complications of Diabetes, Heart diseases, Cancer and Pregnancy) ï‚· Multi organ failure Syndrome (MODS).
  • ï‚· Patients participating in other COVID 19 trials.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Primary Outcome would be measured through Reduction of symptoms and6 months
Recovery of patients from COVID 19 disease in a time bound manner.Conversion of RT PCR negative within first week of accelerated recovery6 months
Secondary Outcome Measures
NameTimeMethod
Possible reduction of viral load data in subjects both at baseline and at 7 days, and 14 days or at recovery or 30 days whichever is earlier..ï‚· Number of days on treatment before recovery and Case fatality rate will also be noted.

Trial Locations

Locations (1)

SRM Medical college Hospital and Research centre

🇮🇳

Kancheepuram, TAMIL NADU, India

SRM Medical college Hospital and Research centre
🇮🇳Kancheepuram, TAMIL NADU, India
Prof M Meenakshi Sundaram
Principal investigator
9940266442
mmssiddha@gmail.com

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