Trend analyses Of Patient-Specific respiratory Physiologal INteractions for weaning decision support
Completed
- Conditions
- Failure to reduce ventilatory supportWeaning failure10024967
- Registration Number
- NL-OMON51035
- Lead Sponsor
- niversiteit Twente
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Informed consent,
2. aged 18 years or older,
3. receiving or expected to receive invasive MV for >48h,
4. ventilated in pressure support mode,
5. SpO2 >= 90% (13),
6. FiO2 <= 60% (13),
7. 0 >= Richmond Agitation Sedation Scale (RASS-score) >= -4
Exclusion Criteria
1. a medical history of neurological disease that might affect the respiratory
drive or neural conduction,
2. BMI > 30 kg/m²,
3. pregnant,
4. moribund,
5. persistent pneumothorax.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary outcome measure is the time in days between the first measurement,<br /><br>which takes place within 24 h of initiation of PS ventilation, and successful<br /><br>weaning (Twean). Successful weaning is defined as the patient being liberated<br /><br>from mechanical ventilation at least 48 h without requiring resumption of MV.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary outcome measures are ICU (TICU) and hospital stay (Thospital).</p><br>