DOSE ranging in UPper limb rehabilitation post stroke (DOSE-UP): Phase I trial

niversity of Melbourne0 sites200 target enrollmentFebruary 24, 2020

Overview

No summary available.

Registry

who.int

Start Date

February 24, 2020

End Date

TBD

Last Updated

last year

Study Type

Interventional

Sex

All

Sponsor

niversity of Melbourne

•\-Current inpatient at time of recruitment,
•\-Hospital diagnosis of stroke (ischemic or haemorrhagic) confirmed on clinical scanning (CT/MRI),
•\-Acute to early subacute phase of recovery, between 3 to 14 days post stroke onset,
•\-Aged 18 years or over,
•\-Upper limb impairment consistent with manual muscle testing of shoulder abduction and finger extension (SAFE) score of 2 to 7,
•\-Able to follow basic one stage commands in English,
•\-Able to provide written informed consent; note, family or authorised representative consent will be sought from individuals with insufficient comprehension to consent, defined by a score \> 5 on Short Portable Mental State test, and
•\-Appropriate candidate for therapy in the home if required.
•\-Discharged from the inpatient hospital setting,
•\-Diagnosis of stroke (ischemic or haemorrhagic),

•\-Had a previous stroke(s) with residual deficits at current stroke onset,
•\-Diagnosis of other neurological conditions (e.g., dementia, Parkinson’s Disease, MS)
•\-Palliation of comorbid medical illness which in the opinion of the treating neurologist, it is deemed unlikely the patient will be able to actively participate in training,
•\-Concomitate condition that would interfere with participation (e.g., undergoing radiotherapy),
•\-Planned discharged to a location other than the community, Melbourne Health, Austin Health and Western Health, or
•\-Unable to commit to the upper limb training regimen.
•\-Had a previous stroke(s) with residual motor deficits,
•\-Diagnosis of other neurological conditions (e.g., dementia, Parkinson’s Disease, MS)
•\-Concomitate condition that would interfere with participation (e.g., undergoing a treatment radiotherapy), or
•\-Unable to travel and commit to the upper limb training regimen.