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临床试验/NCT02294890
NCT02294890Unknown不适用

Does Fibrosis Diathesis Influence the Recovery of Knee Mobility After Total Knee Replacement?

University Hospital Pellenberg0 个研究点目标入组 60 人开始时间: 2015年1月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
60
主要终点
Additional procedures/interventions to gain motion

研究概览

简要总结

At the standard follow-up moment one year after primary TKA for gonarthrosis, all patients will be checked for signs of fibrosis diathesis. This will be done by examining their hands for Dupuytren's nodules and contractures and recording risk factors associated with increased severity and risk of recurrence of Dupuytren's contracture. These include family history, bilateral DD, and ectopic lesions, age of onset less than 50 years, male gender, Ledderhose disease, first ray involvement, multiple ray involvement and ectopic fibromatosis.

This way, two groups of patients will be identified: those with and those without signs of fibrosis diathesis. For both groups, the range of motion (ROM) of the operated knee at 3 and 6 months will be retrieved in the charts, the ROM at 12 months will be measured at that time. Also, additional procedures performed to increase ROM postoperatively will be retrieved from the charts (e.g. continuous passive motion, mobilization under anesthesia). Other causes for knee stiffness will have to be recorded, since these will be the most important exclusion criteria.

In the patients with clear signs of finger contractures, any impression of increase of contracture over the past 12 months will be recorded.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
50 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •All patients undergoing a total knee replacement for primary gonarthrosis with a minimum follow-up of 1 year

排除标准

  • •Patients undergoing a TKA for other reasons than primary gonarthrosis, e.g. after infection, posttraumatic arthritis,hemophilia,...
  • •Patients who had other problems after their TKA resulting in knee stiffness, e.g. infection, bleeding,...

结局指标

主要结局

Additional procedures/interventions to gain motion

时间窗: 12 months

Range of movement of the operated knee at 12 months postoperatively

时间窗: 12 months

次要结局

  • - Increase of contracture or appearance of the nodules and contractures in the hand after the knee surgery.(12 months)
  • KSS score for knee function(12 months)

研究者

发起方
University Hospital Pellenberg
申办方类型
Other
责任方
Principal Investigator
主要研究者

Maarten Van Nuffel

Fellow

University Hospital Pellenberg

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