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Clinical Trials/NCT07242339
NCT07242339Not yet recruitingNot Applicable

Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Plus Biceps Femoris Short Head Block in Patients Undergoing Knee Arthroscopy: A Prospective Randomized Controlled Trial

Kanuni Sultan Suleyman Training and Research Hospital1 site in 1 country50 target enrollmentStarted: November 20, 2025Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
50
Locations
1
Primary Endpoint
Total Opioid Consumption (Tramadol, mg)

Study Overview

Brief Summary

This prospective, randomized, controlled, and multicenter clinical study aims to compare the postoperative analgesic efficacy of two regional anesthesia techniques commonly used in knee arthroscopy: adductor canal block (ACB) and combined adductor canal block plus biceps femoris short head (ACB+BiFeS) block. The study will evaluate postoperative pain control, opioid consumption, adverse effects, hospital stay, and patient satisfaction. Findings will help determine the most effective and safe method for postoperative analgesia in knee arthroscopy patients.

Detailed Description

Knee arthroscopy is one of the most common orthopedic procedures and is frequently associated with significant postoperative pain. Effective multimodal analgesia is therefore essential to reduce opioid consumption, improve early mobilization, and enhance overall patient recovery. Among the regional anesthesia techniques, the adductor canal block (ACB) is well established as an effective motor-sparing block that provides analgesia to the medial and anterior aspects of the knee. However, patients often continue to experience posterolateral knee pain, which is not consistently relieved by ACB alone.

Recent anatomical and cadaveric studies have described the biceps femoris short head (BiFeS) block as a promising technique for targeting the posterolateral knee compartment. The BiFeS block involves deposition of local anesthetic between the short head of the biceps femoris muscle and the lateral femoral cortex at the supracondylar level. Preliminary findings suggest that this block may provide effective analgesia for the posterolateral knee without causing significant motor impairment.

This prospective, randomized, controlled, multicenter clinical trial is designed to evaluate whether the addition of the BiFeS block to standard ACB improves postoperative analgesia compared with ACB alone in patients undergoing knee arthroscopy under spinal anesthesia. The study will investigate pain scores at rest and during movement, total opioid consumption, side effects, rescue analgesic requirements, and quality of recovery. The dermatomal distribution of the blocks will be optionally assessed using cold testing.

By directly comparing ACB and combined ACB+BiFeS block under standardized perioperative conditions, this study seeks to generate high-quality evidence on the clinical utility of BiFeS as an adjunct technique. The results are expected to guide anesthesiologists in selecting optimal regional analgesia strategies for knee arthroscopy, with the potential to improve patient satisfaction, reduce opioid-related complications, and shorten hospitalization.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Supportive Care
Masking
Double (Participant, Outcomes Assessor)

Masking Description

Participants will be blinded to group allocation. Outcome assessors recording pain scores, opioid consumption, and side effects will be blinded to the intervention. The anesthesiologists performing the blocks cannot be blinded due to the nature of the procedures.

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Age ≥ 18 years
  • •ASA physical status I-III
  • •Scheduled for elective knee arthroscopy under spinal anesthesia
  • •Ability to provide written informed consent

Exclusion Criteria

  • •Coagulopathy or bleeding diathesis
  • •Current use of anticoagulant therapy
  • •Known allergy or contraindication to local anesthetics used in the study
  • •History of diabetes mellitus with neuropathy or other neuropathic disorders
  • •Contraindications to regional anesthesia techniques
  • •Refusal to participate

Arms & Interventions

Adductor Canal Block (ACB)

Active Comparator

Participants will undergo ultrasound-guided adductor canal block at the end of surgery under spinal anesthesia.

Intervention: Adductor Canal Block (ACB) Only (Procedure)

Adductor Canal Block + Biceps Femoris Short Head Block (ACB+BiFeS)

Active Comparator

Participants will undergo both adductor canal block and biceps femoris short head block at the end of surgery under spinal anesthesia.

Intervention: biceps femoris short head block + Adductor Canal Block (ACB) (Procedure)

Outcomes

Primary Outcomes

Total Opioid Consumption (Tramadol, mg)

Time Frame: 24 hours

The total dose of tramadol administered via intravenous patient-controlled analgesia (PCA) device within the first 24 hours postoperatively will be recorded in milligrams.

Secondary Outcomes

  • Postoperative Pain with Movement and at rest (NRS)(At 0, 6, 12, and 24 hours after surgery)
  • Rescue Analgesia Requirement(Within the first 24 hours postoperatively)
  • Incidence of Nausea and Vomiting(Within the first 24 hours postoperatively)
  • Quality of Recovery (QOR-15 score)(At 24 hours after surgery)
  • Dermatomal Spread of Block(2nd hour postoperatively)
  • Motor Blockade Incidence(Within the first 24 hours postoperatively)
  • Postoperative Pain with Movement and at rest (NRS)(At 0, 6, 12, and 24 hours after surgery)
  • Rescue Analgesia Requirement(Within the first 24 hours postoperatively)
  • Incidence of Nausea and Vomiting(Within the first 24 hours postoperatively)
  • Quality of Recovery (QOR-15 score)(At 24 hours after surgery)
  • Dermatomal Spread of Block(2nd hour postoperatively)
  • Motor Blockade Incidence(Within the first 24 hours postoperatively)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Engin Ihsan Turan

principal investigator

Kanuni Sultan Suleyman Training and Research Hospital

Study Sites (1)

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