NCT00159640终止2 期
A Multi-Center, Randomized, Double Blind, Dose-Response, Placebo And Gabapentin Controlled Study Of PD-217,014 In The Treatment Of Postherpetic Neuralgia
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 终止
- 发起方
- Pfizer
- 入组人数
- 315
- 试验地点
- 32
- 主要终点
- To characterise the effectiveness of PD-217,014 in the treatment of chronic pain. A numerical pain intensity rating scale is used to assess pain and a mean endpoint (week 4) pain score change from baseline is calculated.
研究概览
简要总结
The purpose of this study is to determine the effectiveness of PD-217,014 in the treatment of chronic pain following a shingles infection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must have pain present for more than 3 months after the healing of shingles skin rash.
- •Patients at screening must have a score >=40 mm on the pain visual analogue scale.
排除标准
- •Patients with poor renal function.
- •Patients with other severe pain, that may impair the self-assessment of the pain due to shingles.
- •Patients with abnormal electrocardiogram.
结局指标
主要结局
To characterise the effectiveness of PD-217,014 in the treatment of chronic pain. A numerical pain intensity rating scale is used to assess pain and a mean endpoint (week 4) pain score change from baseline is calculated.
次要结局
- - Assess the effect of PD-217,014 on responder rate based on the primary endpoint, mean endpoint sleep interference score and the SF-McGill questionnaire (change from baseline to week 4)
研究者
研究点 (32)
Loading locations...
相似试验
已完成
2 期
A Study To Investigate The Effect Of PD-217,014 On Abdominal Pain/Discomfort In Patients With IBS.Irritable Bowel SyndromeNCT00139672Pfizer330
已完成
3 期
Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy Versus D064 or D702 MonotherapyEssential HypertensionNCT06121518Chong Kun Dang Pharmaceutical235
终止
2 期
Safety and Effectiveness of Giving L-743,872 to Patients With Thrush That Has Not Been Cured With FluconazoleCandidiasis, OralHIV InfectionsNCT00005920Merck Sharp & Dohme LLC70
已完成
2 期
An Effectiveness And Safety Study Of PD 0299685 For The Treatment Of Symptoms Associated With Interstitial CystitisInterstitial CystitisPainful Bladder SyndromeNCT00739739Pfizer161
撤回
2 期
Proof-of-concept Study of Forward Pharma (FP)187 in Patients With Mild/Moderate Psoriatic ArthritisPsoriatic ArthritisNCT02475304Skane University Hospital