Phase Angle as a Marker of Muscle Damage, Muscle Fatigue and Inflammation, After Eccentric Exercise
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 28
- Locations
- 2
- Primary Endpoint
- Phase angle
Study Overview
Brief Summary
The purpose of this study will be to assess the effectiveness of bioimpedance device (BIA) as a safe, rapid, and non-invasive method of analyzing muscle damage induced by high intensity induced eccentric exercise as an alternative measurement tool against traditional assessment methods.
A sample of 28 sedentary subjects will be recruited, all participants will perform an eccentric exercise protocol.
Measurements will be done before performing the exercise protocol, immediately after finishing the protocol, 3h after the end of the exercise protocol, 24h after the end of the exercise protocol and 48h after the end of the exercise protocol.
The variables analyzed in all subjects will be phase angle, creatinkinase, jumping strength, VAS scale, white blood count cell, quadriceps muscle thickness, Borg scale and anxiety and depression questionnaires.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy subjets
- •Sedentary subjects
Exclusion Criteria
- •Trained subjects
- •Subjects with musculoskeletal pathology
- •Previous Surgeries in the last 6 months
- •Subjects under pharmacological treatment
Outcomes
Primary Outcomes
Phase angle
Time Frame: change from baseline to 72 hours
The phase angle, which is measured via bioelectrical impedance analysis (BIA), InBody 770 ,is a clinically important bioimpedance parameter used for nutritional assessment and evaluating the risk of various diseases. The phase angle was calculated automatically by the BIA device from these two components according to the following formula: phase angle (°) = (reactance/resistance) × (180°/π).
Secondary Outcomes
- Creatinkinase (CK concentration)(change from baseline to 72 hours)
- cellular inflammatory markers(change from baseline to 72 hours)
- Pain: VAS(change from baseline to 72 hours)
- Quadriceps thickness(change from baseline to 72 hours)
- Leg power(change from baseline to 72 hours)