Assessment of Right Ventricular 2d-strain in Acute Respiratory Distress Syndrome
Completed
- Conditions
- ARDS
- Registration Number
- NCT02638844
- Lead Sponsor
- Central Hospital, Nancy, France
- Brief Summary
Assessment of right ventricular (RV) function in patients with acute respiratory syndrome (ARDS) is warranted because RV failure is frequent and associated with worse outcome. Transthoracic echocardiography is the cornerstone of RV assessment but it remains challenging. Quantification of RV deformation by speckle-tracking imaging echocardiography (STE) is a widely available and reproducible technique that readily provides an integrated analysis of all segments of the RV. This study aims to investigate the accuracy of STE-derived strain parameters in assessing RV function during ARDS.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 49
Inclusion Criteria
- patients with moderate or severe ARDS (Berlin definition)
- receiving mechanical ventilation (>48h estimated length)
- Transthoracic echocardiography performed during the first 36h after ICU admission
Exclusion Criteria
- pregnancy
- protected or deprived of Liberty major
- chronic respiratory disease
- history of clinical right heart failure
- chronic heart failure with LVEF < 35%
- severe valvular heart disease
- under 18 or protected-adults
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measure of longitudinal peak systolic strain up to 36 hours after Intensive Care Unit admission
- Secondary Outcome Measures
Name Time Method Ventilator-free days 28 days Mortality 28 days Measure of PaO2/FiO2 ratio up to 36 hours after Intensive Care Unit admission
Trial Locations
- Locations (1)
Lemarie Jeremie
🇫🇷Nancy, France