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Clinical Trials/CTRI/2024/08/071856
CTRI/2024/08/071856
Not yet recruiting
Phase 1/2

To evaluate and compare the in-vivo safety and efficacy of the skin care formulations in terms of reduction in Acne (live/occurring) on healthy female subjects

Cureskin1 site in 1 country72 target enrollmentStarted: August 11, 2024Last updated:

Overview

Phase
Phase 1/2
Status
Not yet recruiting
Sponsor
Cureskin
Enrollment
72
Locations
1
Primary Endpoint
Reduction in Acne

Overview

Brief Summary

The objective of this study will be to evaluate and compare the in-vivo safety and efficacy of the skin care formulations in terms of reduction in Acne (live/occurring) on healthy female subjects.

 Products: Regime1 and Regime 2

 The evaluation is performed using: Subject Self Evaluation (SSE),  Dermatological : Cosmetic Acceptability, Dermatological Evaluation: Efficacy

 The study lasts 28 days following the first application of the regime on whole face.

 POPULATION - 72 Females subjects will be selected for the study.

The subjects selected for this study are healthy females, aged between 18 and 30 years, having mild to moderate acne and oily to mixed oily skin type.

The study will be conducted in 2 groups.

I. Group A: This group will include 36 female subjects using Regime 1.

II. Group B: This group will include 36 female subjects using Regime 2.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 30.00 Year(s) (—)
Sex
Female

Inclusion Criteria

  • Indian female subjects
  • Healthy subjects
  • Skin is healthy on the studied anatomic unit (free of eczema, wounds, inflammatory scar….) 4 Having mild to moderate acne and oily to mixed oily skin type.

Exclusion Criteria

  • Being pregnant or breastfeeding or having stopped to breastfeed in the past three months
  • Having refused to give her/his assent by not signing the consent form
  • Taking part in another study liable to interfere with this study
  • Being insulin-dependent diabetic or non-insulin-dependent diabetic with a recent therapy (less than 6 months)
  • Having a progressive asthma (either under treatment or last fit in the last 2 years)
  • Having a chronic dermatosis liable to modify the cutaneous reactivity on the tested area (except for specific studies on a determined dermatosis)
  • Having non stabilized thyroid problems (requirement of a stabilized treatment for at least 6 months)
  • Being epileptic.
  • Following a chronic medicinal treatment comprising any of the following products: aspirin-based products, anti-inflammatories, anti-histamines, corticotherapy, taken by general or local routes (the only medication permitted is paracetamol)
  • Having cutaneous hypersensitivity.

Outcomes

Primary Outcomes

Reduction in Acne

Time Frame: Baseline, Day 14, Day 28

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Cureskin
Sponsor Class
Other [fmcg]
Responsible Party
Principal Investigator
Principal Investigator

Dr Pooja Yadav

MASCOT-SPINCONTROL India Pvt. Ltd.

Study Sites (1)

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