Single-centre Prospective Study on the Identification of Clinical, Laboratory, Anatomopathological and Molecular Characteristics for the Future Management of Patients With Neoplasms of the Gastro-intestinal Tract
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Overall Survival
研究概览
简要总结
The aim of the present study is to research histological and molecular markers in patients with neoplasia of the gastrointestinal tract.
详细描述
The aim of the present study is to search for histological and molecular markers in patients with neoplasia of the gastrointestinal tract.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 years or older;
- •PS ECOG 0-2;
- •Histological diagnosis of cancer of the gastro-enteric district: intestinal, pancreatic, biliary tract neoplasms;
- •Radiological evidence of resectable/locally advanced/metastatic disease on the date of the first visit;
- •Availability of tumour histological material;
- •At least one visit following the first oncological visit.
排除标准
- •Absence of histological diagnosis of neoplasm of the gastro-enteric tract;
- •Lack of histological specimens on which to perform examinations.
研究组 & 干预措施
Patients undergoing molecular analysis
Patients undergoing molecular analysis
干预措施: Molecular analyses (Diagnostic Test)
结局指标
主要结局
Overall Survival
时间窗: 48 months
The primary objective of the study is to evaluate the probabilitỳ of survival in terms of OS in relation to the expression of specific anatomopathological, immunohistochemical and molecular markers (GATA6, GemPred Molecular Signature and FOLFIRINOX Molecular Signature) present in the tumour tissue of patients with neoplasms of the gastro-enteric district in the setting of resectable/metastatic disease.
次要结局
未报告次要终点