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临床试验/NCT03973060
NCT03973060已完成不适用

Effectiveness of Muscular Work in Strength Gain of Ischiofemoral and Quadriceps: Relationshionship of Genetic Variants in Improvement of Explosive Force

Universidad Francisco de Vitoria0 个研究点目标入组 80 人开始时间: 2015年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
80
主要终点
Jump power

研究概览

简要总结

In the field of sports training and recovery, the work of muscular strength has become the star theme in terms of its influence on the performance of athletes. In fact, in relation to the training of the inferior members, the scientific evidence indicates that, to increase the other two physical qualities conditioned (speed and resistance), it is necessary to work and to increase the muscular strength.

Randomized intervention trial with sample size of 80 subjects divided into 4 groups (n = 20) of muscular work: concentric, eccentric, concentric-eccentric and isometric. Ages between 21-23 years.

For all the above, the investigators will study as a main objective analyze what type of muscular work is most effective in order to improve some variables of the performance of explosive muscular strength, and to try to determine if that improvement is due, exclusively to the developed training or to the genetics of the subjects and compare the results obtained in the variables of vertical jump, power of saint, horizontal jump and speed 60 meters, before and after the execution of each one of the muscular works dynamic among themselves, and compared to the muscular work isometric.

详细描述

In the field of sports training and recovery, the work of muscular strength has become the star theme in terms of its influence on the performance of athletes. In fact, in relation to the training of the inferior members, the scientific evidence indicates that, to increase the other two physical qualities conditioned (speed and resistance), it is necessary to work and to increase the muscular strength.

To this end, numerous training methods have been developed, in which research and technology provide new solutions that favor and enhance the muscular work done.

Therefore, in the performance of an athlete this work of force influences, and what this implies: type of muscular contraction, way of working that contraction, recruitment of the muscular fiber, and modality of muscular strength developed. But, this performance, it appears that it can also be influenced by environmental parameters such as diet, technological support and genetic factors. It has been discovered in the human genome 12 million of polymorphisms, but it is only recorded that some 214 may have influence on physical qualities, and all of them, the most studied in terms of their influence on sports performance are: genes Muscular, and more specifically the ACTN3, and vasomotor genes that affect the production of energy and that intervene in metabolic processes (ACE gene).

  • Design: Randomized intervention clinical trial, double blinded.
  • Sample: by contrast of hypothesis, a sample size of 80 subjects divided into 4 groups (n = 20) of muscular work: concentric, eccentric, concentric-eccentric and isometric. They were randomized using excel software. As criteria of inclusion, subjects that did not present musculoskeletal lesions in the lower train at the time of the study, which showed a serious commitment to perform the entire muscle training, which were not subject to another type of plan Training that could interfere with the results obtained from the measurement of the study variables, and that would not have been diagnosed with hypertension.
  • Methodology:

The duration of the muscular work was 12 consecutive days, measuring before and after the same variables indicated below.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

盲法说明

The participant was blinded not knowing the treatment to which he was submitted and outcome assessor responsible for collecting the results, without commenting on the group from which the patient came. Only the principal investigator knew the group to which the patient belonged.

入排标准

年龄范围
21 Years 至 23 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Subjects that did not present musculoskeletal lesions in the lower train at the time of the study.
  • Subjects that showed a serious commitment to perform the entire muscle training.
  • Subjects not subject to another type of training plan that could interfere with the results obtained from the measurement of the study variables.

排除标准

  • Subjects with high blood pressure.

研究组 & 干预措施

Concentric muscular work

Experimental

4 series of 12 repetitions of concentric muscular work, with one minute rest between each repetitions, total working time of 24 minutes.

干预措施: Concentric-eccentric muscular work (Device)

Concentric muscular work

Experimental

4 series of 12 repetitions of concentric muscular work, with one minute rest between each repetitions, total working time of 24 minutes.

干预措施: Genetic polymorphism (Genetic)

Eccentric muscular work

Experimental

4 series of 12 repetitions of eccentric muscular work, with one minute rest between each repetitions, total working time of 24 minutes.

干预措施: Concentric-eccentric muscular work (Device)

Eccentric muscular work

Experimental

4 series of 12 repetitions of eccentric muscular work, with one minute rest between each repetitions, total working time of 24 minutes.

干预措施: Genetic polymorphism (Genetic)

Concentric-eccentric muscular work

Experimental

4 series of 12 repetitions of concentric-eccentric muscular work, with one minute rest between each repetitions, total working time of 24 minutes.

干预措施: Concentric-eccentric muscular work (Device)

Concentric-eccentric muscular work

Experimental

4 series of 12 repetitions of concentric-eccentric muscular work, with one minute rest between each repetitions, total working time of 24 minutes.

干预措施: Genetic polymorphism (Genetic)

Isometric muscular work

Experimental

6 seconds of contraction, with 20 seconds of rest with 24 repetitions, for a total working time of 12 minutes.

干预措施: Concentric-eccentric muscular work (Device)

Isometric muscular work

Experimental

6 seconds of contraction, with 20 seconds of rest with 24 repetitions, for a total working time of 12 minutes.

干预措施: Genetic polymorphism (Genetic)

结局指标

主要结局

Jump power

时间窗: Changes from baseline and at the end of procedure (12 days)

Mechanical power in jump tests were measured by estimated (indirect way) from a subject's jump height and body mass, by means of Sayers equation.

Vertical jump

时间窗: Changes from baseline and at the end of procedure (12 days)

The protocol followed for the measurement was; First time: When the patient was barefoot, he placed himself sideways to a smooth wall and raised his right arm with his hand flat on the wall; The distance from the ground to the third finger of the hand (H1) was then measured. Second time: The subject was impregnated the third finger of the right hand in blue chalk powder, separated 10 centimeters from the wall and made a jump back movement with freedom to flex the lower limbs to the 90 º and move the arms, to consecutively and without any pause make a maximum vertical jump. Subsequently, this new distance was measured. This jump was made three times with a break between jump and jump of 45 seconds, and the average of the three (H2) was obtained. Third time: The value of the vertical jump was H = h1-h2.

Horizontal jump

时间窗: Changes from baseline and at the end of procedure (12 days)

On a smooth and horizontal surface, different marks were made distanced one meter each. In the first mark the subject was placed with the feet slightly separated at the height of the hips. Then a first test jump was made; To do so, the subject was told to swing with his arms and bending his knees, he had to jump forward with the greatest possible power. Once this first Test jump was made, the second measurement was carried out, the result of which was taken into account. This result was obtained in centimeters by means of measuring tape, with a precision of one millimeter (mm), and having as points of reference the first mark and the heel of the foot more retarded. The jump was not valid if the first mark was exceeded with the feet before taking off from the ground.

60 meters sprint

时间窗: Changes from baseline and at the end of procedure (12 days)

On an unobstructed sand surface, a distance of 60 meters was pointed out. The measurement in seconds of this variable was obtained by means of a stopwatch.

次要结局

  • ACTN3 polymorphism(Baseline.)
  • ACE polymorphism(Baseline.)

研究者

发起方
Universidad Francisco de Vitoria
申办方类型
Other
责任方
Principal Investigator
主要研究者

David Varillas Delgado

Research Unit Director

Universidad Francisco de Vitoria

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