Occupational Hand Eczema - Testing of a Prevention-concept
- Conditions
- Occupational Contact Dermatitis
- Interventions
- Other: Treatment at the skin department at Gentofte Hospital
- Registration Number
- NCT04790799
- Lead Sponsor
- National Allergy Research Center, Denmark
- Brief Summary
Randomised controlled trial examining the effect of decreased waiting time for the first doctors' appointment, patient education, glove counselling and counselling at departments of social or occupational medicine on severity of hand eczema, quality of life, use of corticosteroids, and jobsituation 3-12 months after intervention in patients with suspected occupational contact dermatitis of the hands.
- Detailed Description
Patients with suspected occupational hand eczema are recruited to the study on basis of their referral from general practitioner to dermatologist. Patients are randomised to either control or intervention group. The control group is treated and followed-up by the dermatologist they have been referred to, while the intervention group is treated and followed-up at Gentofte Hospital skin department with a maximum waiting time of 3 weeks. At the skin department at Gentofte Hospital, the patients in the intervention group receive patient education in prevention and treatment of hand eczema, glove counselling, personal product screening by a chemistry engineer, extended allergy testing and the standard treatment of hand eczema. Patients in both the control and intervention group are asked to fill out a questionnaire at 3, 6, 9 and 12 months after inclusion in the study. The questionnaire contains questions about quality of life, severity of hand exzema, jobsituation, use of healthcare service and use of medicine. Furthermore, prescriptions of medicine are registered in both control and intervention group at 3, 6, 9 and 12 months.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
- Referred from a general practitioner to a dermatologist
- Hand eczema within the last 3 months
- Suspicion that the hand eczema is work-related (either patient and/or doctors suspicion)
- Does not read and write danish
- Severe psychiatric illness
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Intervention group Treatment at the skin department at Gentofte Hospital Treatment in a hospital setting at Gentofte Hospital skin department with patient education, glove counselling, personal product screening by a chemistry engineer, extended allergy testing and the standard treatment of hand eczema.
- Primary Outcome Measures
Name Time Method Change in severity of handeczema assessed by the photographic guide for severity of handeczema Change between baseline and 12 months Self-assessed photographic guide
Change in severity of handeczema assessed by the hand eczema severity index (HECSI) 0-360 points (0 best, 360 worst) Change between baseline and 3 months The hand eczema severity index (HECSI)
Number of participants with loss of job within the last year Baseline Self-repported loss of job wihtin the last year
Amount of corticosteroids prescribed within the last 3 months 12 months Amount of corticosteroids prescribed within the last 3 months
Health-Related Quality of Life assessed by Skindex-29, scale ranging from 0-100 points (higher score = higher impact of skin disease on quality of life) 12 months Skindex-29
Change in severity of handeczema assessed by a visual analog score 0-100 (0 best, 100 worst) Change between baseline and 12 months Visual analog Score for severity of handeczema
Amount of corticosteroids prescribed within the last year Baseline Amount of corticosteroids prescribed wihtin the last year
Health-Related Quality of Life assessed by "European Quality of Life - 5 Dimensions" (EQ-5D) 12 months "European Quality of Life - 5 Dimensions" (EQ-5D)
Health-Related Quality of Life assessed by Dermatology life quality index (DLQI) 0-30 (higher score = higher impact of skin disease on quality of life) 12 months Dermatology life quality index (DLQI)
Number of participants with loss of job within the last 3 months 12 months Self-repported loss of job within the last 3 months
Amount of sick leave within the last 3 months 12 months Self-repported amount of sick leave within the last 3 months
Number of participants with change of occupation due to occupational contact dermatitis within the last year Baseline Change of occupation due to occupational contact dermatitis within the last year
Amount of sick leave within the last year Baseline Self-repported amount of sick leave within the last year
Number of participants with change of occupation due to occupational contact dermatitis within the last 3 months 12 months Change of occupation due to occupational contact dermatitis within the last 3 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Gentofte Hospital, Skin department
🇩🇰Hellerup, Denmark