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Integrated Case Management for Burns Care in Pakistan

Not Applicable
Recruiting
Conditions
Burns
Depression
Anxiety
Unintentional Burn Injury
Interventions
Behavioral: Integrated case manager care
Registration Number
NCT06559501
Lead Sponsor
Pakistan Institute of Living and Learning
Brief Summary

To test whether a culturally adapted multicomponent intervention for improving burns care and patient/family rehabilitation is effective in improving survival among burn victims in Pakistan and is cost-effective. The comparator will be usual care plus brief written self-help advice (enhanced usual care). The study is designed as a multicentre, pragmatic, parallel group, individually randomised trial. Participants in the intervention arm will receive 8 sessions delivered by the case managers (6 low-intensity sessions lasting 30-60 minutes in the hospital/community and 2 follow-up sessions lasting 30 minutes in the community). Assessments will be conducted at baseline, at 3 months, 6 months and at 12-months post-intervention.

Detailed Description

The Burns trial will be conducted in six cities of Pakistan; Karachi, Hyderabad, Lahore, Rawalpindi, Peshawar and Quetta to compare integrated intervention with enhanced usual care. Participants will be randomized either to the intervention or enhanced usual care. The intervention consists of multiple culturally adapted components such as psychological bundle, emergency care, surgical and rehab bundle to improve care within burn units, transitional care, and patient and family rehabilitation (known as 'Integrated case management for improved psychosocial and physical rehabilitation of burn survivors and their families'). The comparator will be usual care (emergency, surgical and rehab care ) plus brief written self-help booklets will be given(enhanced usual care).

The intervention will be carried out by case managers (trained allied health professionals such as nurses, physiotherapists, psychologists etc) and will be started during hospital stay to enhance physical health outcomes by educating patients about self-care/ medications and adherence to treatment resources provided to the case managers and upon discharge to the participants and their carers.

Participants in the intervention arm will receive 8 sessions delivered by the case managers (6 low-intensity sessions lasting 30-60 minutes in the hospital/community and 2 follow-up sessions lasting 30 minutes in the community). Assessments will be conducted at baseline, at 3 months, 6 months and at 12-months post-intervention.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
1146
Inclusion Criteria
  • Adults 18 years and over
  • Accidental burn injury and meet the criteria for admission to burn centres
  • Clinician judgment for participation readiness
  • Ability to provide informed consent
Exclusion Criteria

No intentional burn injuries

• Lacking capacity to provide informed consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Integrated case manager careIntegrated case manager carecomprises 8 sessions delivered by case managers. Case managers will provide up to 6 low-intensity sessions in the hospital or the community (if the patient is discharged before completing the required sessions), with content and duration tailored to patient preferences. Post-discharge, patients will receive 2 follow-up sessions with case managers to ensure a smooth transition into the community.
Primary Outcome Measures
NameTimeMethod
Hierarchical composite score of all-cause mortality, all cause hospital readmissions and health related quality of life (EQ5D)Baseline to 12th month post randomization

all-cause mortality followed by readmission rates and changes in health-related quality of life

Secondary Outcome Measures
NameTimeMethod
Burns Specific Health ScaleBaseline to 3 months, 6 months and 12-months post-intervention

To quantify dysfunction and distress across six major domains of health, specifically burn injury related morbidity

Rosenburg Self-Esteem ScaleBaseline to 3 months, 6 months and 12-months post-intervention

A 10 item self-report instrument to measure individual self-esteem

Visual Analogue ScaleBaseline to 3 months, 6 months and 12-months post-intervention

It provides subjective magnitude estimation and consists of a straight line with limits that carry a verbal description of each extreme of the symptom both pain relief or pain severity

International Trauma QuestionnaireBaseline to 3 months, 6 months and 12-months post-intervention

It is a brief,18 item self-report questionnaire used to assess core features of Post-Traumatic Stress Disorder (PTSD) and Complex PTSD.

Perceived Stigma QuestionnaireBaseline to 3 months, 6 months and 12-months post-intervention

It is used to measure stigmatizing behaviors commonly reported by people with appearance distinctions. Participants were asked to rate how often they experienced a behavior on a 5-point Likert scale

WHO disability assessment scheduleBaseline to 3 months, 6 months and 12-months post-intervention

It is used to measure the impact of health condition, functioning, disability, monitor the effectiveness of interventions as well as the burden of disease both mental and physical disorders

Vancouver Scar ScaleBaseline to 3 months, 6 months and 12-months post-intervention

It is used to document change in scar appearance. Index measures the scares on four parameters, Pigmentation, vascularity, pliability and heigh

Quality of life scale EQ-5DBaseline to 3 months, 6 months and 12-months post-intervention

Health-related quality of life as measured for mobility, self-care, usual activities, pain/discomfort and anxiety/depression

Patient Health Questionnaire (PHQ-9)Baseline to 3 months, 6 months and 12-months post-intervention

To screen, diagnose, monitor and measure the severity of depression

Trial Locations

Locations (12)

Burn Unit, Sandeman Provisional Hospital

🇵🇰

Quetta, Baluchistan, Pakistan

Allied Burn and Reconstructive Surgery Centre

🇵🇰

Faisalābad, Punjab, Pakistan

Pak Italian Modern Burn and Plastic Surgery Centre

🇵🇰

Multān, Punjab, Pakistan

Allied Burn & Reconstructive Surgery Centre

🇵🇰

Faisalābad, Pakistan

Plastic Surgery and Burn Unit, BMC, Quetta

🇵🇰

Quetta, Balochistan, Pakistan

Burns and Plastic Surgery Center, Peshawar

🇵🇰

Peshawar, KPK, Pakistan

Department of Plastic, Reconstructive Surgery and Burn Unit, Kind Edward Medical University

🇵🇰

Lahore, Punjab, Pakistan

Jinnah Burn & Reconstructive Surgery Centre, Lahore

🇵🇰

Lahore, Punjab, Pakistan

Burn Centre, Civil Hospital Hyderabad

🇵🇰

Hyderabad, Sindh, Pakistan

Burn Centre, Ruth K. M. Pfau, Civil Hospital Karachi

🇵🇰

Karachi, Sindh, Pakistan

Burns and Plastic Surgery, Patel Hospital, Karachi

🇵🇰

Karachi, Sindh, Pakistan

Burn Care Centre, PIMS, Islamabad

🇵🇰

Islamabad, Pakistan

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