Ultrasound of Carotid and Femoral Plaque Burden and Non-alcoholic Fatty Liver Disease as Predictors of Cardiovascular Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 21,029
- 试验地点
- 1
- 主要终点
- Carotid and femoral plaque burden cardiovascular (CV) predictive ability beyond NORRISK-2
研究概览
简要总结
The P-SONAR study is a large, observational, prospective cohort study. The overall aim of the study is to investigate whether plaque burden estimation by 2D ultrasound of the carotid and femoral arteries may enhance cardiovascular risk prediction beyond NORRISK-2
详细描述
Design: The P-SONAR Study is a prospective cohort study of all men and women aged 45-74 years attending a health check at one of 10 ultrasound clinics in Norway.
Time schedule: Study inclusion and baseline examinations took place in the period April 2022- March 20025.
Current status: Ultrasound follow-up examinations take place from January 2025 - December 2029.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Persons attending a health check during the study period.
排除标准
- •If they do not consent to participate
结局指标
主要结局
Carotid and femoral plaque burden cardiovascular (CV) predictive ability beyond NORRISK-2
时间窗: From enrollment to an average of 10 years
Additative ability of carotid and femoral plaque burden assessed by ultrasound to predict incident cardiovascular events, beyond conventional risk factors by NORRISK-2
May plaque burden predict incident cardiovascular disease.
时间窗: From enrollment to an average of 10 years.
Find best cutoff value of wTPT plaque burden to predict incident CV disease, across different age groups and sex.
次要结局
未报告次要终点
研究者
Jonn Terje Geitung
Professor
University of Oslo