The clinical study of effect of pregabalin to functional Magnetic Resonance Imaging (fMRI) and Iowa Gambling task (IGT) in postherpetic neuralgia patients

Completed

• Conditions: Postherpetic neuralgia; Nervous System Diseases; Postzoster neuralgia

• Registration Number: ISRCTN55574777
• Lead Sponsor: Xinhua Hospital (China)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-10-28
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Age greater than 60 years and over 40kg of body weight
2. Pain history is longer than 3 months
3. Pain on Visual Analogue Scale (VAS) >3 (0-10 VAS scale), the frequency of acute pain flares occurred more than 3 times per day
4. Refractory to formal treatment such as antiepileptic medicine, antidepressants, opioids and physical treatments and epidural block
5. No history of severe liver and renal diseases

Exclusion Criteria

1. Withdraws from the study
2. Poor effect, intolerant to the study
3. Uncooperative and unable to finish the self evaluation (VAS, qulaity of life [QOL] and SF-36)
4. Coagulation disturbances
5. Allergies to drug
6. Malignancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified