A STUDY TO COMPARE THE EFFICACY OF INTRAVENOUS DEXMEDETOMIDINE AND CLONIDINE IN SUPRESSION OF HAEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND TRACHEAL INTUBATIO
Not Applicable
Completed
- Conditions
- Health Condition 1: null- ASA grade 1 & 2 patients posted for surgery under general anaesthesia
- Registration Number
- CTRI/2016/08/007191
- Lead Sponsor
- ady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
ASA grade I &II, undergoing elective surgery under general anaesthesia with endotracheal intubation
Exclusion Criteria
•Anticipated Difficult intubation(MPG III/IV)
•Emergency surgical procedure
•BMI >30
•Patients with any systemic disease
•Refusal by the patient
•H/O allergy to any drug
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of intravenous dexmedetomidine & clonidine as adjuvants to low dose opioid (fentanyl) in attenuating the haemodynamic response to laryngoscopy and tracheal intubation in patients undergoing surgery under general anaesthesiaTimepoint: Heart rate and mean blood pressure were recorded as baseline(before study drug), after study drug at 5,10 & 15 mins, after I.V. induction, at intubation (0 min), 1, 3, 5, 10 and 15 mins after intubation
- Secondary Outcome Measures
Name Time Method 1.To compare the dose requirement of opioid (fentanyl) and other anaesthetic agents (thiopentone) in all three groups. <br/ ><br>2. To compare the duration of postoperative analgesia. 3. To look for side effects, if any. <br/ ><br> <br/ ><br>Timepoint: from the start of study drug upto the postoperative period