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Clinical Trials/CTRI/2024/07/070389
CTRI/2024/07/070389CompletedNot Applicable

Diaphragmatic function assessment by ultrasonography in paediatric LDLT Recipients

Dr. Rela Institute and medical center1 site in 1 country50 target enrollmentStarted: July 16, 2024Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
50
Locations
1
Primary Endpoint
To evaluate the utility of diaphragmatic function assessment by ultrasonography in the weaning process of children following liver transplantation

Study Overview

Brief Summary

All pediatric LDLT recipients will undergo DIaphragmatic function Assessment by ultraSonography on POD 1,2,3 and then once every week until successful extubation. Data regarding general demographics, anthropometry, preoperative factors, intraoperative details such blood loss, duration of surgery, fluid, blood and products administration, graft details, closure details, postoperative details such as fluid balance, vasopressor requirements, sepsis, ventilatory parameters, nutritional status and weaning attempts will be collected.

Study Design

Study Type
Observational

Eligibility Criteria

Ages
1.00 Month(s) to 18.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • All pediatric LDLT recipients aged 18 years and below.

Exclusion Criteria

  • Patients with known history of diaphragmatic palsy, Intraoperative diaphragmatic injury, patients with prolonged ventilation for moe than 7 days prior to transplant.

Outcomes

Primary Outcomes

To evaluate the utility of diaphragmatic function assessment by ultrasonography in the weaning process of children following liver transplantation

Time Frame: WEEK 1

Secondary Outcomes

  • to evaluate the factors that contribute to delayed weaning in children following LT(week 1, week 2)

Investigators

Sponsor
Dr. Rela Institute and medical center
Sponsor Class
Private hospital/clinic
Responsible Party
Principal Investigator
Principal Investigator

Dr Susan Paulin

Dr. Rela Institute & Medical center

Study Sites (1)

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