Multicenter prospective observational study on the effectiveness of palliative radiotherapy for gastric cancer with bleeding (JROSG 17-3)
- Conditions
- Gastric cancer with bleeding
- Registration Number
- JPRN-UMIN000029580
- Lead Sponsor
- Japanese Radiation Oncology Study Group (JROSG)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 55
Not provided
1) Gastric cancer or locally recurrent gastric cancer after surgery was previously irradiated. 2) Patients planned to receive curative treatment for gastric cancer. 3) Patients received chemotherapy or molecular targeted therapy within 2 weeks before the planned start date of radiotherapy. 4) Patients planned to receive chemotherapy or molecular targeted therapy within 2 weeks after the planned start date of radiotherapy. 5) Patients receiving anticoagulation therapy. 6) Platelet count was less than 25,000/mm3 within 14 days before enrollment. 7) Patients with disseminated intravascular coagulation. 8) Patients with severe comorbidity (infection, heart failure, liver failure, renal failure, or connective tissue disease). 9) Patients with severe mental disease. 10) Pregnant, lactating, or planning to get pregnant during the study period.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of enrolled patients who achieve hemostasis four weeks after enrollment (intention-to-treat analysis)
- Secondary Outcome Measures
Name Time Method Proportion of enrolled patients who complete the planned radiotherapy, Adverse events, Change in hemoglobin level, Change in blood transfusion amount, Symptom score, Satisfaction with the intervention, Rebleeding-free interval, Overall survival, Salvage treatment for hemostasis, Performance status