Retrospective study of the prognosis of Japanese patients with pulmonary hypertensio
Not Applicable
Recruiting
- Conditions
- pulmonary hypertension
- Registration Number
- JPRN-UMIN000026985
- Lead Sponsor
- agoya University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
Since this study is a retrospective study, we investigate all the cases which satisfy the inclusion criteria.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In this study, primary end point is composite endpoint which meets the either criteria of the followings. 1) all cause death (cardiovascular death/ non-cardiovascular death) 2) worsening of pulmonary hypertension worsening of pulmonary hypertension is defined as a condition which meets both of the criteria as follows: a) worsening of the symptom due to pulmonary hypertension, b) necessity of adding oral pulmonary vasodilators, intravenous inotropes or intravenous vasopressors. worsening of the symptom due to pulmonary hypertension is defined as a condition which meets either criteria as follows: a) worsening of WHO functional class, b) worsening of the symptom due to rright heart failure and diuretics dose needs to be increased. 3) Necessity of any treatment as follows: atrial septostomy, lung transplantation, initiation of treatment with IV or SC prostanoids.
- Secondary Outcome Measures
Name Time Method 1) death due to PH or hospitalization due to worsening of PH 2) worsening of the symptom due to pulmonary hypertension 3) change of hemodynamic parameters 4) change of the symptom using questionare. (PM-ADL8/SF-8/HADS) 5) change of laboratory examination 6) change of echocardiographic parameters 7) change of pulmonary function test 8) tapering or withdrawal of home oxygen therapy