Reduced Port Laparoscopic Gastrectomy for Gastric Cancer

Not Applicable

Recruiting

• Conditions: Gastrectomy; Laparoscopic
• Interventions: Procedure: Reduced port laparoscopic gastrectomy

• Registration Number: NCT04295473
• Lead Sponsor: Nanchong Central Hospital

Brief Summary

Reduced port laparoscopic gastrectomy has been adopted in clinical. The safety and outcome of reduced port laparoscopic gastrectomy has not been systematically evaluated. The investigators sought to compare the short and long-term outcome of patients with gastric cancer who underwent reduced port gastrectomy with patients underwent traditional laparoscopic gastrectomy

Detailed Description

Reduced port laparoscopic gastrectomy has been adopted in clinical. The safety and outcome of reduced port laparoscopic gastrectomy has not been systematically evaluated. The investigators designed a comparative study, which sought to compare the short and long-term outcome of patients with gastric cancer who underwent reduced port gastrectomy with patients underwent traditional laparoscopic gastrectomy. The short-term outcome include surgical complications, postoperative morbidity, postoperative nutrition. The long-term outcome mainly include long-term survival.

Study Timeline

• Study First Submitted: 2020-02-29
• Study Start: 2020-03-02
• Study First Submitted QC: 2020-03-02
• Study First Posted: 2020-03-04
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-16
• Last Update Posted: 2025-05-21
• Primary Completion: 2027-03-01
• Study Completion: 2027-03-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

1. Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages.
2. Eastern Cooperative Oncology Group performance status of 0 or 1.
3. Adequate organ function.

Exclusion Criteria

1. Patients had distant metastasis.
2. oesophageal invasion of more than 3 cm.
3. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma.
4. Previous chemotherapy or radiation therapy for any other malignancies.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Reduced port laparoscopic gastrectomy	Reduced port laparoscopic gastrectomy	The definition of reduced port laparoscopic gastrectomy was 1-3 ports used in laparoscopic gastrectomy for gastric cancer.

Primary Outcome Measures

Name	Time	Method
3-year survival rate	3 years	Survival rate for patients with gastrectomy after reduced port laparoscopic gastrectomy
5-year survival rate	5 years	Longterm survival for patients with gastrectomy after reduced port laparoscopic gastrectomy

Secondary Outcome Measures

Name	Time	Method
Malnutrition rate	6 months	Malnutrition rate for patients with gastrectomy after reduced port
Postoperative morbidity rate	6 months	Postoperative morbidity rate for patients with gastrectomy after reduced port laparoscopic gastrectomy
Quality of life in PGSAS-45 scale	12 months	The quality of life were assessed using PGSAS-45 scale for patients with gastrectomy after reduced port laparoscopic gastrectomy.

Trial Locations

Locations (1)

Yunhong Tian; 🇨🇳 Nanchong, Sichuan, China