Danish Breast Cancer Group Internal Mammary Node Study
Not Applicable
Active, not recruiting
- Conditions
- Breast Cancer
- Interventions
- Radiation: Internal mammary node irradiation
- Registration Number
- NCT06549920
- Lead Sponsor
- Danish Breast Cancer Cooperative Group
- Brief Summary
The DBCG IMN study is a nationwide prospective population-based cohort study allocating node-positive breast cancer patients with right-sided tumors to internal mammary node irradiation (IMNI) and patients with left-sided tumors to no IMNI.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 7630
Inclusion Criteria
- Patients with macrometastatic node-positive breast cancer treated with loco-regional radiotherapy.
Exclusion Criteria
- Prior malignancies, bilateral breast cancer, neoadjuvant systemic therapy, recurrence before radiotherapy, and non-standard radiotherapy.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Internal mammary node irradiation Internal mammary node irradiation Patients with right-sided breast cancer tumors were allocated to internal mammary node irradiation.
- Primary Outcome Measures
Name Time Method Overall survival 15-years. Censored at end of study or by emigration.
- Secondary Outcome Measures
Name Time Method Breast cancer mortality 15-years. Censored at end of study or by emigration.
Distant recurrences 15-years. Censored at end of study or by emigration. Death by any cause was regarded as competing event.