Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child

Not Applicable

Withdrawn

• Conditions: Dental Caries
• Interventions: Dietary Supplement: Probiotics in infant milk formula

• Registration Number: NCT01424852
• Lead Sponsor: University of Turku

Brief Summary

Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy.

Hypothesis: the administration of probiotics during infancy has no effect on future dental health.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-08-26
• Study First Submitted QC: 2011-08-26
• Study First Posted: 2011-08-29
• Study Start: 2012-01
• Status Verified: 2012-02
• Last Update Submitted: 2012-02-21
• Last Update Posted: 2012-02-22
• Primary Completion: 2012-12
• Study Completion: 2012-12

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Child participated in the probiotic milk intervention study in early 2000
• Child lives now within 100 km from Turku

Exclusion Criteria

• Child has a chronic illness affecting dental health
• Child lives now outside 100 km from Turku

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Probiotics in milk formula	Probiotics in infant milk formula	B. lactis BB-12 and L. rhamnosus GG delivered in milk formula during the first year of infancy
Control milk formula	Probiotics in infant milk formula	The children received milk formula with no probiotics

Primary Outcome Measures

Name	Time	Method
Caries occurence	10 years

Secondary Outcome Measures

Name	Time	Method
Oral microbial colonization	10 years

Trial Locations

Locations (1)

University of Turku; 🇫🇮 Turku, Finland