Effect Of Exercise Training In Patients With Lung Cancer During Chemotherapy Treatment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Forced Expiratory Volume in 1 second (FEV1)
研究概览
简要总结
To determine the effects of exercise training in patients with lung cancer during chemotherapy treatment. In currently accessible literature, majority studies, met-analysis, and systemic reviews are related to surgical procedures and post-op pulmonary Rehabilitation of patients with Lung cancer. In literature, Gap related to the control group was observed also. The current study aimed to fulfill this gap by planning a structured intervention plan for the control group as well. It will also add in literature the deficiency of oncology rehab for patients receiving chemotherapy only.
详细描述
Literature suggested that a pulmonary rehabilitation program for patients with non-small cell lung cancer undergoing induction chemo-radiotherapy seems to improve respiratory function. It is particularly recommended for smokers and patients with respiratory impairment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed patients of stage 1 and 2 Non-small cell lung carcinoma (NSCLC) including Adenocarcinoma & squamous cell carcinoma The diagnosis was established within 6 wk prior to enrollment and was confirmed by histology.
- •Participants are undergoing lung cancer chemotherapy Participant has the willingness to participate in training WHO physical fitness scores 0-1 Able to perform 6-minute walk test (6MWT) at baseline
排除标准
- •• Participant with history of trauma and surgery
- •Patients with lung disease other than lung cancer
- •Uncontrolled hypertension or unstable coronary artery disease.
- •Severe OA, bone or CNS metastases.
- •hemoglobin <10 g/dL
- •Lower than 3,500 white blood cells per microliter of blood
研究组 & 干预措施
Interventional Group
Pulmonary exercises + Aerobic training, 40%-60% intensity 3 days/ week for 4 weeks
干预措施: Aerobic training (Other)
Control group
Pulmonary exercises, 3 sessions per week and 3-5 repetitions in a session for 4 weeks.
干预措施: Pulmonary Exercises (Other)
结局指标
主要结局
Forced Expiratory Volume in 1 second (FEV1)
时间窗: 4 weeks
Changes from the Baseline, the digital spirometer is used in clinical setting to analyze Forced Expiratory Volume in 1 second FEV1 in Liters
Forced vital Capacity (FVC)
时间窗: 4 weeks
Changes From the Baseline, the digital spirometer is used in clinical setting to analyze Forced vital Capacity in Liters
6 min walk test: Distance (meters)
时间窗: 4 weeks
Changes from the baseline, 6 min walk test (6 MWT) was used to measure Functional capacity. It is a sub maximal exercise test which can aid in assessing functional capacity of patients with cardiopulmonary diseases, in this test we find out the maximum distance in meters which an individual covers in 6 min without any support.
Rate of perceived exertion (RPE)
时间窗: 4 weeks
Changes From the Baseline, measured through Borg RPE scale which measures a person's perception of their effort and exertion breathlessness, and fatigue during physical work rating between 1 and 10. The higher the number, the more intense the exercise. An RPE of 1 is often referred to as just above rest, hardly any exertion, while an RPE of 10 is a maximal effort.
次要结局
- Hospital Anxiety and Depression(4 weeks)
- Mindfulness(4 weeks)