Efficacy of interferon alpha 2b in treatment of ocular surface squamous neoplasia
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- Effectiveness of Interferon alpha 2b in resolution of the OSSN lesion (both clinically and on slit-lamp examination)
研究概览
简要总结
This is a prospective, interventional, open-label, single-arm clinical study designed to evaluate the efficacy and safety of topical Interferon Alpha-2b in patients diagnosed with Ocular Surface Squamous Neoplasia (OSSN). The study aims to assess the rate of complete clinical resolution of OSSN lesions following treatment with Interferon Alpha-2b eye drops, as well as secondary outcomes including time to resolution, recurrence rate, adverse effects, and patient tolerability.
Patients meeting the inclusion criteria will receive topical Interferon Alpha-2b over a specified treatment period and will be regularly monitored through slit-lamp examination and photographic documentation. The study will provide important data on the therapeutic role of Interferon Alpha-2b in managing OSSN, potentially offering a non-surgical treatment alternative.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 15.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Clinically diagnosed cases of Ocular Surface Squamous Neoplasia.
排除标准
- •Patient already undergoing other ongoing / incomplete treatment were excluded from the study.
结局指标
主要结局
Effectiveness of Interferon alpha 2b in resolution of the OSSN lesion (both clinically and on slit-lamp examination)
时间窗: 6 months of Interferon treatment
次要结局
- Time to Clinical Resolution(Recurrence Rate)
研究者
Akash khiyani
Aravind Eye Hospital