CTRI/2023/12/060718
Not yet recruiting
未知
A prospective study to identify clinically relevant biomarkers for early detection of progression analysis of NAFLD to NASH - NI
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Strand Life Sciences Private Limited
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Affected Arm:
- •1\.Clinically confirmed ? NAFLD with significant fibrosis (LSM \=8\.2 kPa), NAFLD with advanced fibrosis (\=9\.7 kPa), and NAFLD\-cirrhosis (\=13\.6 kPa) ? cases based on the following (as available):
- •2\.Adults aged 18 years to 75 years
- •3\.Adults capable of giving a written informed consent to participate
- •4\.Fibroscan, Ultrasound, CT, or MR imaging confirming hepatic steatosis
- •5\.Fibroscan (or histological) evidence of Significant fibrosis (LSM \=8\.2 kPA), or Advanced Fibrosis (\=9\.7 kPa), or cirrhosis (LSM \=13\.6 kPa)
- •6\.BMI Kg/m2 \- 18 and above
- •Control Arm:
- •1\.Cases that are NAFLD without significant fibrosis
- •2\.Adults aged 18 years to 75 years
Exclusion Criteria
- •1\.Patients not consenting or unable to give an informed written consent
- •2\.Recent long\-term (12 months or more) or concomitant use of agents known to cause hepatic steatosis (systemic use of corticosteroids, amiodarone, methotrexate, tamoxifen, tetracycline, high dose oestrogens, valproic acid)
- •3\.Patients not meeting the inclusion criteria or judged by the investigator to be unsuitable for inclusion into the study
- •4\.Patients having concomitant Hepatitis B, or Hepatitis C or any other etiology of liver disease
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Prospective study to evaluate clinical significance of the WGA(white globe appearance) in the gastric lesionsGastric lesions with suspected gastric cancerJPRN-UMIN000013650Ishikawa prefectural central hospital1,000
Recruiting
Not Applicable
A prospective study to evaluate the clinical utility of liquid biopsy in cancer patients underwent tissue based comprehensive genome profiling.solid tumorJPRN-UMIN000041722ational cancer center130
Not yet recruiting
Phase 2
Optimal dose of centchroman in management of cyclical mastalgiaHealth Condition 1: M95-M95- Other disorders of the musculoskeletal system and connective tissueCTRI/2024/08/072215ttar Pradesh University of Medical Sciences
Completed
Not Applicable
Can yoga reduce the need of medication after surgery?Health Condition 1: null- CholelithiasisCTRI/2018/01/011355self funded452
Not yet recruiting
Not Applicable
A prospective study to evaluate the clinical significance of pancreatic elasticity measurement during chemotherapy for pancreatic cancerpancreatic cancerJPRN-UMIN000038763agoya University Graduate School of Medicine40