Cognitive Behavioural Resource-based Therapy of Early Dementia in the Everyday Setting
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Functional ability in the everyday context
研究概览
简要总结
A randomized, controlled, parallel-group trial to evaluate the efficacy of a cognitive behavioral therapy for patients with early dementia.
详细描述
The KORDIAL study is a randomized, controlled, parallel-group trial evaluating the efficacy of a cognitive behavioral therapy for patients at the early stage of Alzheimer's disease. The 3-month experimental intervention consists of 12 individual sessions with regular involvement of carers or other patient proxies. Strategies for improving the patient's coping ability and for enhancing their psychological well-being are combined. The primary outcome criterion is functioning in the everyday context after completion of the intervention and after another 6 months. The control condition will be treatment as usual. The study will be conducted in 5 university outpatient units and in 5 specialist offices.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mild dementia (MMSE > 21) in Alzheimer's disease (ICD-10), proxy available
排除标准
- •Acute of unstable psychiatric or physical disease, proxy unavailable
- •Participation in another trial
结局指标
主要结局
Functional ability in the everyday context
时间窗: Baseline, post treatment, 6 months post treatment
次要结局
- Quality of life, depression, neuro-psychiatric symptoms(Same as for primary outcome)