Early degeneration of the bioprothesis after catheter-assisted aortic valve implantation (TAVI)
- Conditions
- I35.0Aortic (valve) stenosis
- Registration Number
- DRKS00026795
- Lead Sponsor
- Med. Klinik II - Kardiologie und AngiologieBerufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 105
Inclusion Criteria
patients with symptomatic, severe Aortic stenosis
and indication for TF-TAVI-procedure
patients agreement
Exclusion Criteria
excluding criteria for TAVI-procedure
inflammatory bowel diseases
pre-existing coagulopathy
pre-existing autoimmune disease
chronic diseases of the hematopoietic system
serum-creatinine level >2,0mg/dl (except patients with chronic kidney disease under dialysis)
hyperthyroidism
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method identification of pro-cogulatory and pro-inflammatory processes that lead to an early valve degeneration
- Secondary Outcome Measures
Name Time Method Changes of the microbioma as an expression of the remodeling of the intestinal biotope