NCT00534391Unknown3 期
Dose Antibiotic Need in Hordeolum After Incision and Curettage? : A Randomized, Placebo-controlled Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Pain scale
研究概览
简要总结
To compare the effectiveness of combined antibiotic ophthalmic solution (neomycin sulfate, polymyxin B sulfate and gramicidin) with placebo (artificial tear) in the treatment of hordeolum after incision and curettage
详细描述
Hordeolum is a common eyelid disease. In case of mass, I&C is required but role of antibiotic after I&C is not clear. It may not need in post drainage period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •at least 5-millimeters hordeolum
- •the onset within 7 days
排除标准
- •previous incision and curettage of the same site within 1 month or more than 3 times
- •lesions in the adjacent areas suggesting of complications associated with hordeolum such as preseptal cellulitis or blepharitis
- •The patients with immunodeficiency, history of bleeding tendency
- •allergy to aminoglycoside, polymyxin B, gramicidin, xylocaine and povidone iodine
研究组 & 干预措施
B
Placebo Comparator
Artificial tear containing antibiotic solution base
干预措施: Artificial tear (Drug)
A
Experimental
combined antibiotic ophthalmic solution (neomycin sulfate, polymyxin B sulfate and gramicidin)
干预措施: neomycin sulfate, polymyxin B sulfate and gramicidin (Drug)
结局指标
主要结局
Pain scale
时间窗: 1,3,7 days after treatment
次要结局
- Mass size and duration of cure(1, 3, 7, 30 days after treatment)
研究者
研究点 (1)
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