Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making

Not Applicable

Recruiting

• Conditions: Alcohol Use; Suicidal Ideation/Behavior

• Registration Number: NCT06845761
• Lead Sponsor: Mark J Rzeszutek, PhD

Brief Summary

The purpose of this single groups trial is to (Aim 1) determine relationships between alcohol use, suicidal thoughts and behaviors (STBs), and behavioral economic decision-making in a community sample (N = 100) of alcohol using adults who are 18 years of age or older, (Aim 2) is to determine factors that predict engagement with a remote intervention (computer based training for cognitive behavioral therapy; CBT4CBT) for alcohol and its effects on alcohol use, STBs, and decision-making with those same adults.

Participants will complete a baseline assessment and be given access for remote, self-guided CBT4CBT modules for alcohol use. Following this, participants will remotely complete three follow-up assessments over three months. This will allow for determination of incidence and predictors of alcohol use and STBs and determination of predictors of engagement and efficacy of a remote intervention for alcohol use in both samples.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-02-19
• Study First Submitted QC: 2025-02-19
• Study First Posted: 2025-02-25
• Status Verified: 2025-05
• Study Start: 2025-05-09
• Last Update Submitted: 2025-05-21
• Last Update Posted: 2025-05-28
• Primary Completion: 2026-01
• Study Completion: 2026-05

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• At least 18 years old
• Consume alcohol at least weekly
• A score of 8 or greater on the Alcohol Use Disorder Identification Test (AUDIT)
• Some interest in cutting back on drinking or quitting
• Read and understand English

Exclusion Criteria

• A score of 31 or greater on the Alcohol Use Disorder Identification Test (AUDIT) at baseline
• Reporting schizophrenia and/or other psychiatric diagnoses other than depression or anxiety at baseline
• Already being in treatment for alcohol use disorder at baseline
• Past month substance use other than cannabis or tobacco

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Change in Alcohol Use	Assessed at study week 0, 4, 8, and 12	Participants will complete baseline and remote follow-up assessments. Alcohol use will be measured by timeline follow-back of alcohol use for the previous 4 weeks of time of assessment. General linear mixed-effects modeling will be used to assess changes in alcohol use.
Engagement with Self-Guided Cognitive Behavioral Therapy for Alcohol Use	Assessed at study week 12	At the end of the study, participant engagement with Computer Based Training for Cognitive Behavioral Therapy (CBT4CBT) modules will be analyzed with ordinary linear regression. Engagement will be defined as the proportion of modules completed.
Change in Suicidal Thoughts and Behaviors	Assessed at study week 0, 4, 8, and 12	Participants will complete baseline and remote follow-up assessments. Suicidal thoughts and behaviors will be will be measured by the Colombia Suicide Severity Rating Scale. Suicidal ideation severity is measured from a scale of 0 to 25, where higher scores indicate higher levels of suicidal ideation severity. General linear mixed-effects modeling will be used to assess changes in suicidal thoughts and behaviors.

Trial Locations

Locations (1)

University of Kentucky; 🇺🇸 Lexington, Kentucky, United States