Study on People with Eye Injuries Sent for Glaucoma Treatment at a South Indian Eye Hospital

Not yet recruiting

• Conditions: Glaucoma secondary to eye trauma,

• Registration Number: CTRI/2025/05/086737
• Lead Sponsor: Aravind Eye Hospital Pondicherry

Brief Summary

This is a prospective cohort study aimed at analyzing the demographic profile, risk factors, clinical presentation, and short-term outcomes of patients referred to glaucoma services following ocular trauma at a tertiary eye hospital in South India. The study will include patients aged above 5 years with a history of ocular trauma and elevated intraocular pressure (IOP) or signs of glaucoma. A minimum of 202 eyes will be enrolled. Detailed ophthalmic evaluations will be conducted at baseline, 10 days, 1 month, and 3 months, including IOP measurements, gonioscopy, fundus examination, and visual field analysis. The study aims to assess the prevalence and mechanisms of post-traumatic ocular hypertension or glaucoma and evaluate the influence of socioeconomic factors, referral patterns, and time to presentation on treatment outcomes. Ethical approval has been obtained, and the study is classified as minor increase over minimal risk as per ICMR guidelines.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-05-20
• Last Update Posted: 2025-09-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 202

Inclusion Criteria

• Patients with a documented history of ocular trauma 2.
• Patients referred to glaucoma services for Evaluation following Ocular Trauma or with IOP more than 21mmHg or has characteristic disc or field changes or patients with gonioscopic abnormalities post trauma.

Exclusion Criteria

• Pre-existing glaucoma or ocular hypertension.
• Systemic conditions affecting IOP 3 Patients with Cognitive Impairment 4 Children with intellectual developmental disorders or children with special needs.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical course and management outcomes of patients referred to Glaucoma Services following ocular trauma, assessed by intraocular pressure (IOP) control , changes at Optic Disc or Gonioscopy changes	Follow up at 10 days, 1 month, 3 months.

Secondary Outcome Measures

Name	Time	Method
1.Prevalence and distribution of different mechanisms leading to post-traumatic ocular hypertension or glaucoma.	2.Impact of socioeconomic factors, referral patterns, and time from trauma to glaucoma service presentation on short-term treatment outcomes.

Trial Locations

Locations (1)

Aravind Eye Hospital ,Pondicherry; 🇮🇳 Pondicherry, PONDICHERRY, India

Aravind Eye Hospital ,Pondicherry

🇮🇳Pondicherry, PONDICHERRY, India

Dr Sanjana Ahuja

Principal investigator

7974761119

sanjana_ahuja21@ymail.com