RAndomised trial aiming to imProve the quality of lIfe of people with Dementia (Alzheimer's disease) plus their carers (RAPID-Plus).

Not Applicable

• Conditions: Depression; Alzheimer's disease; Mental Health - Depression; Neurological - Alzheimer's disease

• Registration Number: ACTRN12616000778482
• Lead Sponsor: WA Centre for Health and Ageing

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-06-15
• Last Update Posted: 5 July 2021

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 132

Inclusion Criteria

The inclusion criteria will be:
For AD participants
* Diagnosis of major neurocognitive disorder due to probable AD
according to DSM-5 criteria
* Mini-mental State Examination (MMSE) score of greater than or equal to 15
* Cornell Scale for Depression in Dementia (CSDD) score greater than or equal to 4
* Availability of a carer willing to participate in the trial
* Fluent in written and spoken English

For Carers, we will include those who:
* Are aged greater than or equal to 18 years
* Are fluent in written and spoken English
* Are free of diseases likely to undermine ongoing participation in the
study for 24 months (e.g., metastatic cancer)
* Do not consume alcohol in excess of 14 standard drinks per week
* Show no evidence of cognitive impairment (MMSE greater than or equal to 24/30)
* Do not meet DSM-5 criteria for major depression
* Show no evidence of active suicidal intent
* Show no evidence of visual impairment that might compromise ability to read or use the computer
* Are registered with a general practitioner

Exclusion Criteria

We will exclude individuals who:
* Meet National Institute of Mental Health criteria for depression in AD
* Have medical conditions that are likely to compromise their ability to
complete the required activities of the study e.g. severe sensory
impairment or life expectancy of < 2 years from time of enrolment
* Consume alcohol in excess of 14 standard drinks per week
* Have no health practitioner who can provide ongoing clinical care
* Decline or are unable to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified