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Clinical Trials/NCT07321340
NCT07321340
Not yet recruiting
Not Applicable

Insole Optimization for Rheumatoid Arthritis Patients - INORA - (Insole Optimization for Rheumatoid Arthritis Patients)

Centre Hospitalier Universitaire de Saint Etienne1 site in 1 country10 target enrollmentStarted: June 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
10
Locations
1
Primary Endpoint
Construction of a patient-specific 3D model reproducing a gait cycle with or without an orthosis.

Overview

Brief Summary

Rheumatoid arthritis affects 0.5% of the population, often leading to foot deformities and pain that are difficult to treat. Management is based on controlling inflammation, adapting footwear and using custom-made insoles, all of which have proven effective. The aim of this research is to build a digital model of plantar pressures based on CT scans, in order to optimize orthopedic insoles. The study will analyze the gait of patients with and without standard insoles to identify mechanical criteria correlated with pain. The ultimate aim is to design optimized insoles, validated by a new gait analysis.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Basic Science
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients with rheumatoid arthritis according to 2010 ACR/EULAR criteria
  • RA at low activity level according to DAS28≤3.2
  • Patient with mechanical forefoot involvement on walking and improved by foot orthoses.

Exclusion Criteria

  • Patients with a contraindication to a bone scan
  • Patients with neurological gait disorders that interfere with gait analysis
  • Exclude particularly protected persons:
  • Pregnant women, parturients, nursing mothers;
  • Persons deprived of liberty, hospitalized without consent, hospitalized for purposes other than research;

Arms & Interventions

3D imaging (foot CT scan)

Other

foot CT scan

Intervention: gait analysis from 3D imaging (ENSENSO) (Other)

Outcomes

Primary Outcomes

Construction of a patient-specific 3D model reproducing a gait cycle with or without an orthosis.

Time Frame: Week 1

Bone geometry from 3D imaging (foot CT) combined with gait analysis (speed, step length, angular variation at the knee and ankle) from 3D imaging (ENSENSO) and accelerometers

Secondary Outcomes

  • Correlation of model parameters with insole-wearing comfort.(Day 1)
  • Correlation of model parameters with pain(Day 1)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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