Structured preparation for alcohol detoxificatio

Not Applicable

Completed

• Conditions: Alcohol misuse; Mental and Behavioural Disorders; Mental and behavioural disorders due to use of alcohol

• Registration Number: ISRCTN14621127
• Lead Sponsor: Surrey and Borders Partnership NHS Foundation Trust

Brief Summary

2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31057808 protocol (added 08/05/2019) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34325743/ (added 02/08/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-02-22
• Study Completion: 2019-11-30
• Last Update Posted: 17 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

1. Presentation to alcohol services seeking abstinence from alcohol
2. Alcohol dependence (moderate to severe), scoring 16 and above on Severity of Alcohol Dependence Questionnaire (SADQ)
3. Stated intention to stay in the area within the time period of the intervention
4. Willingness to be part of a group intervention if randomised to receive it
5. Aged 18 years and over

Exclusion Criteria

1. Age less than 18 (as not usually treated by specialist alcohol services).
2. Pregnancy: Pregnant women need urgent intervention to come off alcohol, due to the effect of alcohol on the foetus.
3. Known terminal illness with life expectancy of less than 6 months.
4. Severe medical condition that requires urgent medical admission, which would lead to an un-planned medically assisted withdrawal.
5. Severe cognitive impairment that compromises capacity and /or ability to participate in a group intervention.
6. Acute stage of severe and enduring mental illness (schizophrenia, Bipolar Affective Disorder, recurrent depressive disorder: current episode severe), when acute symptomatology compromises client’s ability to participate in a group intervention.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Duration of continuous abstinence with no incidents of lapse or relapse is assessed by self-report with the use of Time Line Follow Back method at 3, 6 and 12 months post randomisation.<br> 2. Percentage of Days of Abstinence (PDA) is assessed by self-report with the use of Time Line Follow Back method at 3, 6 and 12 months post randomisation<br> 3. Time to relapse is assessed by self-report from randomisation to first day of alcohol use<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Severity of alcohol dependence is measured using the Severity of Alcohol Dependence Questionnaire (SADQ) at baseline, 3, 6 and 12 months post randomisation<br> 2. Severity of cravings and urges are measured using the Alcohol Urge Questionnaire at baseline, 3, 6 and 12 months post randomisation<br> 3. Changes in cognitive performance is measured using the Incentive Conflict Task (ICT) at baseline, 3, 6 and 12 months post randomisation<br> 4. Participation in aftercare is extracted from clinical notes retrospectively at 3,6 and 12 months post randomisation<br>