Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion
Phase 3
- Conditions
- Induction of Total Intravenous General Anesthesia
- Registration Number
- NCT00146926
- Lead Sponsor
- Hospices Civils de Lyon
- Brief Summary
Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol
Exclusion Criteria
- pregnant
- sedative or analgesic drug 24h before surgery
- allergy with drug used in the study
- difficulty of communication
- absence of informed written consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method After prophylactic solution, evaluation of the pain caused by injection of propofol with a four-point scale before lose of consciousness
- Secondary Outcome Measures
Name Time Method Explicite and implicite memory of pain immediately after surgery and on day one Adverse effects
Trial Locations
- Locations (1)
Grégoire CHATAIN
🇫🇷Lyon, France
Grégoire CHATAIN🇫🇷Lyon, France