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Clinical Trials/NCT00146926
NCT00146926
Unknown
Phase 3

Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

Hospices Civils de Lyon1 site in 1 country200 target enrollmentSeptember 2005
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ConditionsInduction of Total Intravenous General Anesthesia
Drugskétamine 20mgephedrine 3mglidocaine 40mg

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Induction of Total Intravenous General Anesthesia
Sponsor
Hospices Civils de Lyon
Enrollment
200
Locations
1
Primary Endpoint
After prophylactic solution, evaluation of the pain caused by injection of propofol with a four-point scale before lose of consciousness
Last Updated
19 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.

Registry
clinicaltrials.gov
Start Date
September 2005
End Date
TBD
Last Updated
19 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol

Exclusion Criteria

  • •sedative or analgesic drug 24h before surgery
  • •allergy with drug used in the study
  • •difficulty of communication
  • •absence of informed written consent

Outcomes

Primary Outcomes

After prophylactic solution, evaluation of the pain caused by injection of propofol with a four-point scale before lose of consciousness

Secondary Outcomes

  • Explicite and implicite memory of pain immediately after surgery and on day one
  • Adverse effects

Study Sites (1)

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