Effect of an oral health optimized diet on the subgingival biofilm.

Not Applicable

• Conditions: K05.1; K05.3; Chronic gingivitis; Chronic periodontitis

• Registration Number: DRKS00009888
• Lead Sponsor: niklinik Freiburg, Abteilung für Zahnerhaltungskunde und Parodontologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-02-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Consent for participation, mainly carbohydrate-based diet, no interdental cleaning during the study, gingiva index (Löe & Silness) >0,5

Exclusion Criteria

- moderate to severe chronic periodontitis or aggressive periodontitis (in case of a light chronic periodontitis, biofilm sampling will be performed only at probing depths <4mm).
- Smoking
- Infectious or life threatening diseases
- Intake of antibiotics < 6 months before or during the study
- drugs influencing the bleeding or the inflammation like anticoagulants, cortisone etc.
- pregnancy or breastfeeding

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of the biofilm after 6 weeks of dietary change compared to baseline and the control group.

Secondary Outcome Measures

Name	Time	Method
Change of clinical parameters (Plaque index, Gingiva index, probing depths, Attachmentlevel, Bleeding on probing) and serological change (hsCRP, TNF-a, IL-6, Adiponectin) after 6 weeks of dietary change compared to baseline and to the control group.