Microneedle Patch With Botulinum Toxin in Management of Enlarged Facial Pores
Phase 3
Active, not recruiting
- Conditions
- Enlarged Pores
- Registration Number
- NCT06293755
- Lead Sponsor
- Dhurakij Pundit University
- Brief Summary
The purpose of this study is to assess the efficacy and safety of microneedle patch with botulinum toxin for improving enlarged pores.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
- At least 18 years old and concerned about enlarged pores
- Have pore size 0.3-0.6 mm
- Have pore parameter in each other side of faces not different more than 5%
Exclusion Criteria
- Any neuromuscular condition
- Pregnancy or breast feeding
- History of allergy : Botulinum toxin, topical anesthesia
- History of keloid or hypertrophic scar
- History of coagulation or receiving medication that causes coagulation disorder
- Using drugs that have interaction with Botulinum toxin
- Using topical medication that improves enlarged pores in 1 month
- Taking medication that improves enlarged pores in 1 month
- Receiving the laser/treatment/chemical peeling in 6 months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Change from baseline of enlarged pores as measured by VISIA (pores parameter) and using pore score Post-intervention, week 4 and week 16 the used pore scores, patients with visible pores took the score "1," and those with enlarged pores took "2." When black heads were embedded on facial pores the score was "3." The scores were assessed by 2 investigators who were blinded to the treatment used on each side.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie botulinum toxin's effect on sebaceous gland activity in NCT06293755's microneedle patch treatment?
How does microneedle patch delivery of botulinum toxin compare to intradermal injection in Phase 3 trials for pore management?
Which biomarkers predict response to botulinum toxin via microneedle patches versus injections in Dhurakij Pundit University's study?
What adverse events are associated with botulinum toxin microneedle patches versus intradermal injections in Phase 3 trials?
Are there combination therapies involving botulinum toxin microneedle patches and retinoids for managing enlarged pores in clinical research?
Trial Locations
- Locations (1)
Dhurakij Pundit University
🇹🇭Lak Si, Bangkok, Thailand
Dhurakij Pundit University🇹🇭Lak Si, Bangkok, Thailand