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Clinical Trials/NCT02791399
NCT02791399
Completed
Not Applicable

A Patient-Centered Intervention to Improve Opioid Safety

VA Office of Research and Development1 site in 1 country286 target enrollmentMarch 23, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Opioid Safety
Sponsor
VA Office of Research and Development
Enrollment
286
Locations
1
Primary Endpoint
Current Opioid Misuse Measure (COMM)
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This is a randomized controlled trial of a multifaceted intervention designed to improve the safety of opioid prescribing. The specific aims of this study are to: (a) evaluate whether a multifaceted intervention (Improving the Safety of Opioid Prescribing; ISOP) enhances opioid safety, (b) assess whether participation in ISOP impacts the clinician-patient relationship, and (c) explore to what extent ISOP is associated with changes in pain and pain-related function.

Detailed Description

The investigators will randomize primary care providers (PCPs) at the VA Portland Health Care System to either ISOP or the control condition; patients will be nested by clinician status. All PCPs who enroll will participate in either a two-hour educational workshop or the two-hour educational workshop + nurse care manager (NCM). The NCM will maintain a registry of enrolled patients, track opioid medication-related events from the medical record, and provide decision support to PCPs for issues related to prescription opioid safety. The NCM will also meet individually with enrolled participants to discuss strategies for preventing/reducing opioid side effects, preventing diversion, and providing rationale for screening for prescription opioid misuse. The investigators will recruit patients who are already prescribed chronic opioid therapy for chronic non-cancer pain. Participants will be enrolled for one year. Outcomes will be measured at baseline, and 6 and 12 months after enrollment.

Registry
clinicaltrials.gov
Start Date
March 23, 2016
End Date
October 31, 2020
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Enrollment in primary care at the VA Portland Health Care System
  • Receiving long-term opioid therapy (for at least 3 months) for chronic pain unrelated to a life-limiting disease
  • Able to read and write in English

Exclusion Criteria

  • Age younger than 18 years old
  • On opioid therapy for palliative or end-of-life care
  • Current enrollment in an opioid substitution program
  • Lack of access to a telephone

Outcomes

Primary Outcomes

Current Opioid Misuse Measure (COMM)

Time Frame: Data collected at baseline, 6 months, and 12 months.

The Current Opioid Misuse Measure (COMM) is an assessment of self-reported risk of prescription opioid misuse. There are 17 items, each rated on a scale of 0 (never) to 4 (very often). Total scores range from 0 - 68, with higher scores indicating a greater risk of prescription opioid misuse.

Urine Drug Test

Time Frame: Data collected at baseline, 6 months, and 12 months

Participants will complete urine drug tests (UDTs) to evaluate for presence of substances. UDTs will evaluate for cannabis, cocaine, amphetamines, benzodiazepines, barbiturates, opioids, and opiates. Study results are dichotomous.

Secondary Outcomes

  • Chronic Pain Grade(One year)

Study Sites (1)

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