Efficacy of Iron Supplements Given on Alternate Days Versus Consecutive Days in The Treatment of Iron Deficiency Anemia in Women of Reproductive Age: Non-inferiority, Randomized Controlled Trial
Phase 2
Recruiting
- Conditions
- Iron deficiency anemiairon deficiency anemia,iron supplement,iron absorption,hepcidin
- Registration Number
- TCTR20200614001
- Lead Sponsor
- Faculty of medicine, Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 98
Inclusion Criteria
1. Women , age 18-50 yrs
2. Dx of Iron deficiency anemia in
KCMH by Hb < 10 g/dl or decreased in
Hb level > 2 g/dl (if baseline Hb was
known) with serum ferritin < 30 mcg/L
3. No Hx of blood transfusion or
donation in 3 months PTA
Exclusion Criteria
1. Concomitant major chronic diseases or inflammatory diseases
Ex. Chronic kidney disease, Chronic
heart disease, malignancy or poor
controlled DM, morbid obesity, active infection
2. Pregnancy or Lactation
3. Gastrectomy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in hemoglobin at day 30 of treatment The proportion of patients with increased Hb levels > 2 g/dl
- Secondary Outcome Measures
Name Time Method An increase in hemoglobin levels from baseline 3 months Hemoglobin levels,Proportion of patients with hemoglobin turn normal level 3 months Hemoglobin level ,Number of patient with hemoglobin level increase > = 1 g/dl 30 days Hemoglobin level before and after supplement 1 mo ,Serum ferritin levels 30 days and 3 months Mean of serum ferritin after treatment,Compliance 1 month and 3 month visit number of pills intake,drug side effects severity 1 month and 3 month visit nausea vomitting scale, others as record