IRCT20080728001031N32招募中1 期
Evaluation of safety and efficacy of repeated intrathecal and/or intravenous transplantations of Wharton’s jelly derived mesenchymal stromal cells in patients with ALS, clinical trial, phase I
Celltech Pharmed Co.0 个研究点目标入组 12 人开始时间: 待定最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 70 years（—）
- 性别
- All
入选标准
- •Age: 18-70
- •Both gender
- •Disease onset at least: 6 months
- •All patients diagnosed with ALS and R/O of differential diagnosis
- •ALSFRS-R= 25
- •Under treatment with rilozule and edaravone
- •Ability to walk even with aid and ability to tolerate the procedures
排除标准
- •Concomitant psychiatric or cognitive disease
- •Concomitant systemic disease (uncontrolled HTN, uncontrolled DM, uncontrolled kidney diseases, HF, …)
- •Treatment with corticosteroid , IVIg, immunosuppressive and cytotoxic during 12 months
- •Dependency to ventilation
- •History of malignancy
- •Concomitant other neurodegenerative disorders
研究者
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