Heart Rate Variability Monitoring to Predict Hypotension Following Spinal Anesthesia for Cesarean Delivery: Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The change of averaged value
研究概览
简要总结
Based on the patient's heart rate variability, the analgesia nociception index (ANI) measures the activity of the autonomic nervous system and the sympathetic/parasympathetic nervous system and expresses it as a numerical value through a specific algorithm. The investigators will analyze it and see if it has the ability to predict severe hypotension following spinal anesthesia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Adult pregnant women scheduled for cesarean section under spinal anesthesia
排除标准
- •Emergency cesarean section
- •When performing general anesthesia or epidural anesthesia
- •Multiple pregnancies
- •Surgery in which massive hemorrhage and massive blood transfusion are expected due to placenta previa
- •Cardiac arrhythmias, congestive heart failure, ischemic heart disease, congenital heart anomalies
- •Cranial nervous system disease
- •Autonomic nervous system-related underlying diseases not related to pregnancy
- •Fetal malformations
- •Those who have an allergic skin reaction to adhesive substances such as bandages
结局指标
主要结局
The change of averaged value
时间窗: 15 min, 10 min and 5 min before entering the operating room; every 5 min after entering the operating room
The change of averaged value presented in ANI monitor
The change of instantaneous value
时间窗: 15 min, 10 min and 5 min before entering the operating room; every 5 min after entering the operating room
The change of instantaneous value presented in ANI monitor
Total dose of injected phenylephrine
时间窗: During the anesthesia (from initiation of anesthesia until the end of anesthesia)
Total dose of injected glycopyrrolate
时间窗: During the anesthesia (from initiation of anesthesia until the end of anesthesia)
The change of systolic blood pressure
时间窗: Every 1 min after entering the operating room until finishing the operation
次要结局
未报告次要终点
研究者
Hyo-Seok Na
Clinical professor
Seoul National University Bundang Hospital