NCT04053920CompletedNot Applicable
Resistance Exercise Training at Different Intensities in Healthy and Frail Older People: A Feasibility Study
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Glasgow
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Muscle strength
Study Overview
Brief Summary
The aim of the current study, therefore, is to determine the feasibility of recruitment and adherence to resistance exercise training interventions performed at low and high loads, to volitional muscular failure, in a trial population that includes both healthy and frail older people.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 65 Years to — (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Over age of 65 years
Exclusion Criteria
- •Current participation in an exercise programme
- •Exercise deemed unsafe by clinical team
Arms & Interventions
Low load
Experimental
Training at 30-40% one-repetition maximum (1RM)
Intervention: Low Load Resistance exercise (Behavioral)
High load
Experimental
Training at 65-75% one-repetition maximum (1RM)
Intervention: High Load Resistance exercise (Behavioral)
Outcomes
Primary Outcomes
Muscle strength
Time Frame: Change from baseline to 8 weeks
Knee extensor maximal torque during an isometric MVC
Secondary Outcomes
- One-repetition maximum(Change from baseline to 8 weeks)
- Short performance physical battery test(Change from baseline to 8 weeks)
- Muscle strength(Change from baseline to 8 weeks)
- Vastus lateralis muscle thickness(Change from baseline to 8 weeks)
- Biomechanics during walking and stair climbing(Change from baseline to 8 weeks)
- Quality of life measure(Change from baseline to 8 weeks)
Investigators
Stuart Gray
Senior Lecturer in Exercise and Metabolic Health
University of Glasgow
Study Sites (1)
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