Prevalence of Antiphospholipid Antibodies Among Women With Preeclampsia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Rate of positive antiphospholipid antibodies
研究概览
简要总结
The purpose of this study is to determine the prevalence of positive antiphospholipid antibodies among women with preeclampsia and to determine the effect of antiphospholipid antibodies on the severity of preeclampsia and the obstetric outcomes
详细描述
For all women included in the study, blood samples will be tested for anticardiolipin antibodies and lupus anticoagulant. The clinical details of all women will be collected by reviewing their hospital and prenatal records. The following clinical characteristics will be evaluated: maternal age, previous gestations, parity, past or family history of preeclampsia, gestational age at the onset of preeclampsia, gestational age at delivery and birth weight. The following pregnancy and delivery complications will be assessed: placental insufficiency, intrauterine growth restriction, fetal loss (stillbirth) and early neonatal death.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women with preeclampsia.
排除标准
- •Women with systemic autoimmune disease.
- •Women with active thromboembolic disorders.
- •Women with history of previous thromboembolic disorders.
结局指标
主要结局
Rate of positive antiphospholipid antibodies
时间窗: 20 weeks to 42 weeks gestational age
Number of women having positive antiphospholipid antibodies per total number of women
次要结局
未报告次要终点
研究者
Mohamed Sayed Abdelhafez
Dr
Mansoura University