Prevalence of Antiphospholipid Antibodies Among Women With Preeclampsia
- Conditions
- Preeclampsia
- Registration Number
- NCT02699437
- Lead Sponsor
- Mohamed Sayed Abdelhafez
- Brief Summary
The purpose of this study is to determine the prevalence of positive antiphospholipid antibodies among women with preeclampsia and to determine the effect of antiphospholipid antibodies on the severity of preeclampsia and the obstetric outcomes
- Detailed Description
For all women included in the study, blood samples will be tested for anticardiolipin antibodies and lupus anticoagulant. The clinical details of all women will be collected by reviewing their hospital and prenatal records. The following clinical characteristics will be evaluated: maternal age, previous gestations, parity, past or family history of preeclampsia, gestational age at the onset of preeclampsia, gestational age at delivery and birth weight. The following pregnancy and delivery complications will be assessed: placental insufficiency, intrauterine growth restriction, fetal loss (stillbirth) and early neonatal death.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 200
- Pregnant women with preeclampsia.
- Women with systemic autoimmune disease.
- Women with active thromboembolic disorders.
- Women with history of previous thromboembolic disorders.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of positive antiphospholipid antibodies 20 weeks to 42 weeks gestational age Number of women having positive antiphospholipid antibodies per total number of women
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Obstetrics and Gynecology Department in Mansoura University Hospital
🇪🇬Mansoura, Dakahlia, Egypt
Obstetrics and Gynecology Department in Mansoura University Hospital🇪🇬Mansoura, Dakahlia, Egypt