Effect of preoperative Interscalene block on intraoperative anaesthetic requirements in patients undergoing upperarm surgeries under General anaesthesia
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- compare the changes in heart rate,systolic blood pressure and Diastolic blood pressure at before
研究概览
简要总结
Interscalene nerve block (ISB) has been commonly used as a sole anaesthetic technique and also alleviate postoperative pain and provide optimal analgesia during shoulder and upper arm surgeries. Ultrasound-guided interscalene nerve block (UISB) can reduce opioid use and its concomitant opioid-related adverse effects such as pruritus, nausea, vomiting, consciousness disturbance, and constipation. However, these trials focused mainly on the postoperative opioid-sparing effects of nerve blocks and did not show an impact on the intraoperative consumption of volatile anesthetics and opioids .
Desflurane is a newer inhalational anaesthetic with minimal metabolism in the human body, and is associated with rapid recovery.Opioid consumption was reduced using a single ISB at the day of surgery They found that ISB is superior to GA and GA + ISB in patients undergoing shoulder arthroscopy in terms of faster recovery and analgesics consumption.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Adult patients ( 18- 65 yrs) of both genders are included after receiving informed written consent ( Annexure 1) 2.Patients belonging to American Society of Anesthesiologist Class 1-2 (Annexure 3) 3.Patients undergoing upper limb surgeries under General anaesthesia.
排除标准
- •Uncooperative patients
- •Patients with obstructive pulmonary disease,Diabetes,Neuropathy, brachial plexus and radial nerve injury, Contralateral diaphragmatic paralysis, chest wall and lung injury, history of allergy to study drug
- •Patients having contraindications for Interscalene block
- •Patients on antiepileptics,psychotropic drugs,long term analgesics.
结局指标
主要结局
compare the changes in heart rate,systolic blood pressure and Diastolic blood pressure at before
时间窗: Baseline | Preinduction | Post induction | Post Intubation | 5min | 10 min | 15 min | 20 min | 25 min | 30 min | 35 min | 40 min | 45 min | 50 min | 55 min | 60 min | 65 min | 70 min | 75 min | 80 min | 85 min | 90 min | 95 min | 100 min | 105 min | 110 min | 115 min | 120 min | 125 min | 130 min | 140 min | 150 min | 160 min | 170 min | 180 min
,during and after cannulation
时间窗: Baseline | Preinduction | Post induction | Post Intubation | 5min | 10 min | 15 min | 20 min | 25 min | 30 min | 35 min | 40 min | 45 min | 50 min | 55 min | 60 min | 65 min | 70 min | 75 min | 80 min | 85 min | 90 min | 95 min | 100 min | 105 min | 110 min | 115 min | 120 min | 125 min | 130 min | 140 min | 150 min | 160 min | 170 min | 180 min
Compare the VAS score anong the two groups
时间窗: Baseline | Preinduction | Post induction | Post Intubation | 5min | 10 min | 15 min | 20 min | 25 min | 30 min | 35 min | 40 min | 45 min | 50 min | 55 min | 60 min | 65 min | 70 min | 75 min | 80 min | 85 min | 90 min | 95 min | 100 min | 105 min | 110 min | 115 min | 120 min | 125 min | 130 min | 140 min | 150 min | 160 min | 170 min | 180 min
compare the ease of cannulation between two groups.
时间窗: Baseline | Preinduction | Post induction | Post Intubation | 5min | 10 min | 15 min | 20 min | 25 min | 30 min | 35 min | 40 min | 45 min | 50 min | 55 min | 60 min | 65 min | 70 min | 75 min | 80 min | 85 min | 90 min | 95 min | 100 min | 105 min | 110 min | 115 min | 120 min | 125 min | 130 min | 140 min | 150 min | 160 min | 170 min | 180 min
次要结局
- compare the ease of cannulation between two groups.(aseline)
研究者
Dr Nithya
BANGALORE MEDICAL COLLEGE AND HOSPITAL