ISRCTN15928978已完成未知
A prospective, controlled, double blind, international study to assess the effects of strontium ranelate vs placebo on the reduction of periprosthetic bone loss in patients with total hip arthroplasty
Institut de Recherches Internationales Servier (France)0 个研究点目标入组 96 人开始时间: 2011年8月4日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 96
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Caucasian male or postmenopausal women
- •2. Age less than or equal to 50 years
- •3. Patients with conventional primary total hip arthroplasty, cementless femoral stem and primary coxarthrosis as indication for total hip arthroplasty
排除标准
- •1. Short femoral stem
- •2. Any perioperative complication
- •3. Patient with inflammatory arthropathy
- •4. Impossibility to perform Dual-emission X-ray absorptiometry (DXA)
- •5. Increase risk or history of venous thromboembolism (VTE)
- •6. Known hypersensitivity or contraindication to the study drug or Calperos D3®
- •7. Concomittant treatments likely to interfere with bone metabolism
研究者
相似试验
进行中（未招募）
1 期
Efficacy of strontium ranelate in the reduction of bone loss around the metal implants in patients after hip replacement surgery.Reduction of periprosthetic bone loss in patients with total hip arthoplasty for coxarthrosisMedDRA version: 14.1Level: PTClassification code 10052306Term: Periprosthetic osteolysisSystem Organ Class: 10022117 - Injury, poisoning and procedural complicationsEUCTR2010-020215-36-BEInstitut de Recherches Internationales Servier126
进行中（未招募）
不适用
A prospective, controlled, double blind, international study to assess the effects of strontium ranelate vs. placebo on the reduction of periprosthetic bone loss in patients with total hip arthroplastyThe Periprosthetic bone loss” study - The Periprosthetic bone loss” studyReduction of periprosthetic bone loss in patients with total hip arthoplasty for coxarthrosisMedDRA version: 14.1Level: PTClassification code 10052306Term: Periprosthetic osteolysisSystem Organ Class: 10022117 - Injury, poisoning and procedural complicationsEUCTR2010-020215-36-DEInstitut de Recherches Internationales Servier126
进行中（未招募）
不适用
A prospective, controlled, double blind, international study to assess the effects of strontium ranelate vs. placebo on the reduction of periprosthetic bone loss in patients with total hip arthroplasty. The ''Periprosthetic bone loss'' study - The ''Periprosthetic bone loss'' studyReduction of periprosthetic bone loss in patients with total hip arthoplasty for coxarthrosisMedDRA version: 14.0Level: PTClassification code 10052306Term: Periprosthetic osteolysisSystem Organ Class: 10022117 - Injury, poisoning and procedural complicationsEUCTR2010-020215-36-ITINSTITUT DE RECHERCHES INTERNATIONALES SERVIER126
进行中（未招募）
不适用
A prospective, randomized, double-blind, international multicenter trial to investigate the efficacy and safety of NT 201 in comparison to placebo and to compare two different application schemes of NT 201 in the treatment of lateral periorbital wrinkles - NT crow's feetlateral periorbital wrinkles (Crow's feet)MedDRA version: 6.1Level: PTClassification code 10040867EUCTR2006-005396-17-ITMERZ PHARMACEUTICALS GMBH108
进行中（未招募）
1 期
A prospective, randomized, double-blinded, international multicenter trial to investigate the efficacy and safety of NT 201 in comparison to placebo and to compare two different application schemes of NT 201 in the treatment of lateral periorbital wrinkles - NT crow's feetTreatment of lateral periorbital wrinkles (Crow's feet)MedDRA version: 9.1 Level: LLT Classification code 10052611 Term: Crow's feetEUCTR2006-005396-17-GBMerz Pharmaceuticals GmbH108