NCT05946122招募中1 期
Effect of Atorvastatin as a Renal Protection in Patients With Systemic Inflammatory Response Syndrome Using Renal Arterial Resistive Index
Minia University1 个研究点 分布在 1 个国家目标入组 106 人开始时间: 2023年5月30日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 106
- 试验地点
- 1
- 主要终点
- Acute kidney injury
研究概览
简要总结
Offering renal protection in systemic inflammatory response syndrome by atorvastatin
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 25 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients ( male and female) with systemic inflammatory response ( total leucocytic count >12,000 mm3'. temperature >38 C, Heart rate >90 b/min and respiratory rate>20 cycle).
排除标准
- •Hemodynamic instability
- •Pre-admission chronic kidney disease.
- •Intra-vascular coagulopathy
- •Patients with myopathy.
研究组 & 干预措施
Active ( Ator) group
Active Comparator
干预措施: Atorvastatin 40 Mg Oral Tablet (Drug)
control group
Placebo Comparator
干预措施: placebo drug (Drug)
结局指标
主要结局
Acute kidney injury
时间窗: one week
incidence or acute kidney injury
次要结局
- renal resistive vascular index(one week)
- APACHE score ( acute physiology and chronic health evaluation)(one week)
- length of ICU stay(two weeks)
研究者
Mina Maher
lecturer of anesthesia and pain medicine
Minia University
研究点 (1)
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