Inter-observer and Intra-observer Variability of the Wrinkle Test

• Conditions: Wrinkle Test
• Interventions: Diagnostic Test: wrinkle test

• Registration Number: NCT03813758
• Lead Sponsor: HaEmek Medical Center, Israel

Brief Summary

Skin wrinkling of the fingers following immersion in warm water depends on intact sympathetic innervation. It is abolished by lesions affecting both central and peripheral sympathetic pathways. It affords a simple and reliable clinical test of sympathetic function.

Detailed Description

Fingertip skin wrinkling after prolonged immersion in water is a well-recognized phenomenon, whereas a denervated digit does not exhibit normal skin wrinkling while a finger with a regenerated or repaired nerve shows at least partial reappearance of wrinkling. This is the basis for the bedside immersion-wrinkling test of autonomic digital nerve function. The exact mechanism of fingertip skin wrinkling is still subject to controversy. the purpose of this study is to examine the Inter-observer and Intra-observer Variability of the Wrinkle Test.

Study Timeline

• Study First Submitted: 2019-01-16
• Study First Submitted QC: 2019-01-21
• Study First Posted: 2019-01-23
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-05
• Last Update Posted: 2019-08-07
• Study Start: 2019-09-15
• Primary Completion: 2020-01-01
• Study Completion: 2020-01-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• patients after suture of full cut of digital nerve

Exclusion Criteria

• other nerve injury

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
healthy finger	wrinkle test	-
finger after digital nerve cut	wrinkle test	-

Primary Outcome Measures

Name	Time	Method
wrinkle test	40 min	wrinkle of the skin in the finger compaared to the finger witout digital nerve injury

Trial Locations

Locations (1)

HaEmek medical center; 🇮🇱 Afula, Israel