The Impact of High-Fat Ketogenic Diet and Low-Fat Diet in Women Body Weight

Not Applicable

Recruiting

• Conditions: Healthy; Overweight and Obesity
• Interventions: Other: A randomized acute controlled trial of twenty-eight healthy overweight or obese women

• Registration Number: NCT05811702
• Lead Sponsor: King Faisal University

Brief Summary

The aim of this study is investigated the effect of high fat Ketogenic Diet (HFKD) in weight reduction compared to the low-fat diet (LFD) among Saudi overweight and obese women. A randomized acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether HFKD or LFD for 12 weeks.

Detailed Description

Obesity is associated with an increased risk of high blood pressure and heart muscle damage, which leads to cases that increase the chances of developing cardiovascular diseases, and if weight gain is not controlled, these results lead to obesity is the main cause of cardiovascular disease and causes dyslipidemia, high blood pressure and diabetes. Recently, there have been followed systems and programs food some of which are beneficial for health and some of them are unhealthy systems. The diet is one of the most controversial issues. The aim of this study is investigated the effect of high fat Ketogenic Diet (HFKD) in weight reduction compared to the low-fat diet (LFD) among Saudi overweight and obese women. A randomized acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether HFKD or LFD for 12 weeks. Our primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of body weight, the percentage of body fat, The secondary outcomes have evaluated at the percentage of body fat, blood glucose, lipid profile.

Study Timeline

• Study First Submitted: 2023-03-07
• Study First Submitted QC: 2023-03-31
• Study First Posted: 2023-04-13
• Status Verified: 2023-06
• Last Update Submitted: 2023-06-09
• Last Update Posted: 2023-06-12
• Study Start: 2023-07-01
• Primary Completion: 2023-10-01
• Study Completion: 2023-11-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• Healthy Overwight and obese wonen
• aged 18 and 40
• BMI 25 and 34.5 kg m2
• fat parentage above 30% .

Exclusion Criteria

• Man
• women in normal weight or BMI less than 25 and 34.5 kg m2
• Breastfeeding and pregnant women

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
low-fat diet (LFD	A randomized acute controlled trial of twenty-eight healthy overweight or obese women	A randomised acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether LFD for 12 weeks. The weight will be measured weekly, body fat % and blood samples before and after 12 weeks of following LFD.
High fat Ketogenic Diet (HFKD)	A randomized acute controlled trial of twenty-eight healthy overweight or obese women	A randomized acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether HFKD for 12 weeks. The weight will be measured weekly, body fat % and blood samples before and after 12 weeks of following HFKD.

Primary Outcome Measures

Name	Time	Method
percentage of body fat	12 weeks	Primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of percentage of body fat,
Body weight (kg) and BMI	12 weeks	primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of body weight, the percentage of body fat,

Secondary Outcome Measures

Name	Time	Method
Total Cholesterol mg/dl	12 weeks	Secondary outcome of this study to investigated the effective diets HFKD and LFD on total Cholesterol mg/dl
LDL) mg/dl (	12 weeks	LDL) mg/dl (
Hb Aic (%)	12 weeks	Hb Aic (%)
HDL) mg/dl (	12 weeks	HDL) mg/dl (
Glucose (mg/dl)	12 weeks	Glucose (mg/dl)
Triglycerides) mg/dl (	12 weeks	Secondary outcome of this study to investigated the effective diets HFKD and LFD on total Triglycerides) mg/dl (

Trial Locations

Locations (1)

Randah Alqurashi; 🇸🇦 Riyadh, Saudi Arabia