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临床试验/NCT05811702
NCT05811702招募中不适用

The Impact of High-Fat Ketogenic Diet and Low-Fat Diet in the Body Weight and Cardiovascular Risk Factors on Overweight and Obese Saudi Women: A Randomized Controlled Trial.

King Faisal University1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2023年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
28
试验地点
1
主要终点
percentage of body fat

研究概览

简要总结

The aim of this study is investigated the effect of high fat Ketogenic Diet (HFKD) in weight reduction compared to the low-fat diet (LFD) among Saudi overweight and obese women. A randomized acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether HFKD or LFD for 12 weeks.

详细描述

Obesity is associated with an increased risk of high blood pressure and heart muscle damage, which leads to cases that increase the chances of developing cardiovascular diseases, and if weight gain is not controlled, these results lead to obesity is the main cause of cardiovascular disease and causes dyslipidemia, high blood pressure and diabetes. Recently, there have been followed systems and programs food some of which are beneficial for health and some of them are unhealthy systems. The diet is one of the most controversial issues. The aim of this study is investigated the effect of high fat Ketogenic Diet (HFKD) in weight reduction compared to the low-fat diet (LFD) among Saudi overweight and obese women. A randomized acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether HFKD or LFD for 12 weeks. Our primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of body weight, the percentage of body fat, The secondary outcomes have evaluated at the percentage of body fat, blood glucose, lipid profile.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Healthy Overwight and obese wonen
  • aged 18 and 40
  • BMI 25 and 34.5 kg m2
  • fat parentage above 30% .

排除标准

  • women in normal weight or BMI less than 25 and 34.5 kg m2
  • Breastfeeding and pregnant women

结局指标

主要结局

percentage of body fat

时间窗: 12 weeks

Primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of percentage of body fat,

Body weight (kg) and BMI

时间窗: 12 weeks

primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of body weight, the percentage of body fat,

次要结局

  • Total Cholesterol mg/dl(12 weeks)
  • LDL) mg/dl ((12 weeks)
  • Hb Aic (%)(12 weeks)
  • HDL) mg/dl ((12 weeks)
  • Glucose (mg/dl)(12 weeks)
  • Triglycerides) mg/dl ((12 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Randah Miqbil Alqurashi

Assistant professor

King Faisal University

研究点 (1)

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