Randomized Study on the Effects of Moderate Anaemia in Free Microvascular Tissue Transfer

Withdrawn

• Conditions: Open Fracture of Foot; Tumor

• Registration Number: NCT01848431
• Lead Sponsor: University of Zurich

Brief Summary

The evaluation of Perfusion of free flaps in patients with moderate anaemia and possible reduction of the transfusion threshold.

* Trial with surgical intervention

Detailed Description

In study group 1 patients will be kept at a hematocrit level below 28% and only receive transfusions if symptomatic or the fall below 25%. Patients in group 2 will receive transfusions to reach a hematocrit always above 30%.

Tissue perfusion in free flaps will be measured with indocyanine green fluorescence angiography, confocal microscopy and oxygen partial pressure measurement probes.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2013-04-22
• Study Start: 2013-05
• Study First Submitted QC: 2013-05-06
• Study First Posted: 2013-05-07
• Status Verified: 2014-12
• Primary Completion: 2018-01
• Study Completion: 2018-01
• Last Update Submitted: 2020-11-09
• Last Update Posted: 2020-11-10

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of Blood transfusions peri- and postoperative	10 days

Trial Locations

Locations (1)

University Hospital Zurich, Center for Reconstructive Surgery; 🇨🇭 Zurich, ZH, Switzerland